Fertility and infertility: Definition and epidemiology

M Vander Borght, C Wyns - Clinical biochemistry, 2018 - Elsevier
Infertility is a disease characterized by the failure to establish a clinical pregnancy after 12
months of regular and unprotected sexual intercourse. It is estimated to affect between 8 and …

[HTML][HTML] Impact of environmental factors on human semen quality and male fertility: a narrative review

N Kumar, AK Singh - Environmental Sciences Europe, 2022 - Springer
Background Worldwide rising trend in infertility has been observed in the past few years with
male infertility arising as a major problem. One main reason for the rise in male infertility …

Male reproductive disorders and fertility trends: influences of environment and genetic susceptibility

NE Skakkebaek, E Rajpert-De Meyts… - Physiological …, 2016 - journals.physiology.org
It is predicted that Japan and European Union will soon experience appreciable decreases
in their populations due to persistently low total fertility rates (TFR) below replacement level …

Endocrine disrupting chemicals and disease susceptibility

TT Schug, A Janesick, B Blumberg… - The Journal of steroid …, 2011 - Elsevier
Environmental chemicals have significant impacts on biological systems. Chemical
exposures during early stages of development can disrupt normal patterns of development …

The effects of phthalates in the cardiovascular and reproductive systems: A review

M Mariana, J Feiteiro, I Verde, E Cairrao - Environment international, 2016 - Elsevier
Every year millions of tons of plastic are produced around the world and humans are
increasingly exposed to them. This constant exposure to plastics has raised some concerns …

Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring

SF Ng, RCY Lin, DR Laybutt, R Barres, JA Owens… - Nature, 2010 - nature.com
The global prevalence of obesity is increasing across most ages in both sexes. This is
contributing to the early emergence of type 2 diabetes and its related epidemic,. Having …

Paternally induced transgenerational inheritance of susceptibility to diabetes in mammals

Y Wei, CR Yang, YP Wei, ZA Zhao… - Proceedings of the …, 2014 - National Acad Sciences
The global prevalence of prediabetes and type 2 diabetes (T2D) is increasing, and it is
contributing to the susceptibility to diabetes and its related epidemic in offspring. Although …

Metabolic regulation is important for spermatogenesis

L Rato, MG Alves, S Socorro, AI Duarte… - Nature Reviews …, 2012 - nature.com
Male factor infertility is increasing in developed countries, and several factors linked to
lifestyle have been shown to negatively affect spermatogenesis. Sertoli cells are pivotal to …

Effects of PM2. 5 exposure on reproductive system and its mechanisms

L Wang, D Luo, X Liu, J Zhu, F Wang, B Li, L Li - Chemosphere, 2021 - Elsevier
With the development of human society, haze has become an important form of air pollution.
Haze is a mixture of fog and haze, and the main component of haze is fine particulate matter …

[HTML][HTML] Endocrine disrupting chemicals and reproductive health in boys and men

W Rodprasert, J Toppari, HE Virtanen - Frontiers in endocrinology, 2021 - frontiersin.org
Male reproductive health has declined as indicated by increasing rates of cryptorchidism, ie,
undescended testis, poor semen quality, low serum testosterone level, and testicular cancer …