Redox regulation of immunometabolism
J Muri, M Kopf - Nature Reviews Immunology, 2021 - nature.com
Metabolic pathways and redox reactions are at the core of life. In the past decade (s),
numerous discoveries have shed light on how metabolic pathways determine the cellular …
numerous discoveries have shed light on how metabolic pathways determine the cellular …
Naringin and naringenin as anticancer agents and adjuvants in cancer combination therapy: Efficacy and molecular mechanisms of action, a comprehensive narrative …
Z Memariani, SQ Abbas, SS Ul Hassan… - Pharmacological …, 2021 - Elsevier
Although the rates of many cancers are controlled in Western countries, those of some
cancers, such as lung, breast, and colorectal cancer are currently increasing in many low …
cancers, such as lung, breast, and colorectal cancer are currently increasing in many low …
An update of Nrf2 activators and inhibitors in cancer prevention/promotion
F Pouremamali, A Pouremamali, M Dadashpour… - Cell Communication and …, 2022 - Springer
Abstract NF-E2-related factor 2 (Nrf2) protein is a basic-region leucine zipper transcription
factor that defends against endogenous or exogenous stressors. By inducing several …
factor that defends against endogenous or exogenous stressors. By inducing several …
Honey bee products: preclinical and clinical studies of their anti-inflammatory and immunomodulatory properties
HR El-Seedi, N Eid, AA Abd El-Wahed, ME Rateb… - Frontiers in …, 2022 - frontiersin.org
Inflammation is a defense process triggered when the body faces assaults from pathogens,
toxic substances, microbial infections, or when tissue is damaged. Immune and inflammatory …
toxic substances, microbial infections, or when tissue is damaged. Immune and inflammatory …
Regulating Nrf2-GPx4 axis by bicyclol can prevent ferroptosis in carbon tetrachloride-induced acute liver injury in mice
T Zhao, Z Yu, L Zhou, X Wang, Y Hui, L Mao… - Cell death …, 2022 - nature.com
Hepatocellular death is a sensitive parameter for detecting acute liver injury (ALI) of toxic,
viral, metabolic, and autoimmune origin. Ferroptosis has recently been implicated in carbon …
viral, metabolic, and autoimmune origin. Ferroptosis has recently been implicated in carbon …
Redox potential of antioxidants in cancer progression and prevention
S George, H Abrahamse - Antioxidants, 2020 - mdpi.com
The benevolent and detrimental effects of antioxidants are much debated in clinical trials
and cancer research. Several antioxidant enzymes and molecules are overexpressed in …
and cancer research. Several antioxidant enzymes and molecules are overexpressed in …
Recent advances of natural polyphenols activators for Keap1‐Nrf2 signaling pathway
Y Zhou, Z Jiang, H Lu, Z Xu, R Tong… - Chemistry & …, 2019 - Wiley Online Library
Abstract The Keap1‐Nrf2/ARE signaling pathway is an important defense system against
exogenous and endogenous oxidative stress injury. The dysregulation of the signaling …
exogenous and endogenous oxidative stress injury. The dysregulation of the signaling …
Phenolic compounds as Nrf2 inhibitors: potential applications in cancer therapy
J Sharifi-Rad, V Seidel, M Izabela… - Cell Communication and …, 2023 - Springer
Cancer is a leading cause of death worldwide and involves an oxidative stress mechanism.
The transcription factor Nrf2 has a crucial role in cytoprotective response against oxidative …
The transcription factor Nrf2 has a crucial role in cytoprotective response against oxidative …
The Nrf2 pathway in ischemic stroke: a review
Ischemic stroke, characterized by the sudden loss of blood flow in specific area (s) of the
brain, is the leading cause of permanent disability and is among the leading causes of death …
brain, is the leading cause of permanent disability and is among the leading causes of death …
Pharmacological protection against ischemia-reperfusion injury by regulating the Nrf2-Keap1-ARE signaling pathway
Ischemia/reperfusion (I/R) injury is associated with substantial clinical implications, including
a wide range of organs such as the brain, kidneys, lungs, heart, and many others. I/R injury …
a wide range of organs such as the brain, kidneys, lungs, heart, and many others. I/R injury …