Neuromodulation in drug‐resistant epilepsy: a review of current knowledge

T Xue, S Chen, Y Bai, C Han, A Yang… - Acta Neurologica …, 2022 - Wiley Online Library
Nearly 1% of the global population suffers from epilepsy. Drug‐resistant epilepsy (DRE)
affects one‐third of epileptic patients who are unable to treat their condition with existing …

Unexplained Causes of Glioma-Associated Epilepsies: A Review of Theories and an Area for Research

M Saviuk, E Sleptsova, T Redkin, V Turubanova - Cancers, 2023 - mdpi.com
Simple Summary Patients with gliomas experience worsened quality of life due to epileptic
attacks. Over 80% of patients are susceptible to seizures, significantly hindering their …

Identification of different MRI atrophy progression trajectories in epilepsy by subtype and stage inference

F Xiao, L Caciagli, B Wandschneider, D Sone… - Brain, 2023 - academic.oup.com
Artificial intelligence (AI)-based tools are widely employed, but their use for diagnosis and
prognosis of neurological disorders is still evolving. Here we analyse a cross-sectional …

Connectivity and neuronal synchrony during seizures

X Ren, A Brodovskaya, JL Hudson… - Journal of …, 2021 - Soc Neuroscience
There is uncertainty regarding when and which groups of neurons fire synchronously during
seizures. While several studies found heterogeneous firing during seizures, others …

Distinct roles of rodent thalamus and corpus callosum in seizure generalization

A Brodovskaya, T Batabyal, S Shiono… - Annals of …, 2022 - Wiley Online Library
Objective Bilateral synchronous cortical activity occurs during sleep, attention, and seizures.
Canonical models place the thalamus at the center of bilateral cortical synchronization …

Intracranial direct electrical mapping reveals the functional architecture of the human basal ganglia

L Qi, C Xu, X Wang, J Du, Q He, D Wu, X Wang… - Communications …, 2022 - nature.com
The basal ganglia play a key role in integrating a variety of human behaviors through the
cortico–basal ganglia–thalamo–cortical loops. Accordingly, basal ganglia disturbances are …

Characteristics of ictal thalamic EEG in pediatric-onset neocortical focal epilepsy

B Edmonds, M Miyakoshi, LG Remore, S Ahn… - Clinical …, 2023 - Elsevier
Objective To characterize ictal EEG change in the centromedian (CM) and anterior nucleus
(AN) of the thalamus, using stereoelectroencephalography (SEEG) recordings. Methods …

[HTML][HTML] Neuronal circuits sustaining neocortical-injury-induced status epilepticus

T Singh, T Batabyal, J Kapur - Neurobiology of disease, 2022 - Elsevier
Objectives Acute injuries or insults to the cortex, such as trauma, subarachnoid hemorrhage,
lobar hemorrhage, can cause seizures or status epilepticus (SE). Neocortical SE is …

Extrahippocampal seizure and memory circuits overlap

AA Naik, A Brodovskaya, S Subedi, A Akram, J Kapur - eneuro, 2022 - eneuro.org
Seizures cause retrograde amnesia. We have previously demonstrated that seizures erode
recently formed memories through shared ensembles and mechanisms in the CA1 region of …

[HTML][HTML] The role of monoaminergic neurons in modulating respiration during sleep and the connection with SUDEP

LY Gu, Q Yu, Y Shen, YL Wang, Q Xu… - Biomedicine & …, 2022 - Elsevier
Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death among
epilepsy patients, occurring even more frequently in cases with anti-epileptic drug …