[HTML][HTML] Gene co-expression changes underlying the functional connectomic alterations in Alzheimer's disease

B He, P Gorijala, L Xie, S Cao, J Yan - BMC Medical Genomics, 2022 - Springer
Background There is growing evidence indicating that a number of functional connectivity
networks are disrupted at each stage of the full clinical Alzheimer's disease spectrum. Such …

The ABC's of Alzheimer risk gene ABCA7

L Duchateau, N Wawrzyniak… - Alzheimer's & …, 2024 - Wiley Online Library
Alzheimer's disease (AD) is a growing problem worldwide. Since ABCA7's identification as a
risk gene, it has been extensively researched for its role in the disease. We review its …

Untangling huge literature to disinter genetic underpinnings of alzheimer's disease: A systematic review and meta-analysis

HS GNS, VLP Marise, KS Satish, AV Yergolkar… - Ageing Research …, 2021 - Elsevier
Drug discovery for Alzheimer's Disease (AD) is channeled towards unravelling key disease
specific drug targets/genes to predict promising therapeutic candidates. Though enormous …

[HTML][HTML] Assessing the power of exome chips

CM Page, SE Baranzini, BH Mevik, SD Bos, HF Harbo… - PLoS …, 2015 - journals.plos.org
Genotyping chips for rare and low-frequent variants have recently gained popularity with the
introduction of exome chips, but the utility of these chips remains unclear. These chips were …

[HTML][HTML] Non‐invasive brain stimulation for improving cognitive function in people with dementia and mild cognitive impairment

J Zhang, J Liu, J Li, C Zhang, M Qu - The Cochrane Database of …, 2018 - ncbi.nlm.nih.gov
Non‐invasive brain stimulation for improving cognitive function in people with dementia and
mild cognitive impairment - PMC Back to Top Skip to main content NIH NLM Logo Access …

[HTML][HTML] Establishment of TUSMi008-A, an induced pluripotent stem cell (iPSC) line from a 76-year old Alzheimer's disease (AD) patient with PAXIP1 gene mutation

Y Wang, J Zhang, J Hu, G Li, Y Lei, J Zhao - Stem Cell Research, 2019 - Elsevier
A 76-year old Alzheimer's disease (AD) female patient donated her Peripheral blood
mononuclear cells (PBMC). The non-integrating episomal vector system used to reprogram …

A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the …

OJ Conway, I Jansen, MM Carrasquillo… - Acta …, 2019 - eprints.ncl.ac.uk
The genetic variant rs72824905-G (minor allele) in the PLCG2 gene was previously
associated with a reduced Alzheimer's disease risk (AD). The role of PLCG2 in immune …

Imaging Correlates of Heterogeneity in the Syndromes Associated with Frontotemporal Lobar Degeneration

D Whiteside - 2024 - repository.cam.ac.uk
The syndromes associated with frontotemporal dementia are heterogeneous in their
presentation and progression, with variable correlation between clinical phenotype and …

Behavioural disinhibition in the syndromes associated with frontotemporal lobar degeneration

A Murley - 2020 - repository.cam.ac.uk
The different clinical syndromes caused by frontotemporal lobar degeneration (FTLD) have
highly heterogenous and overlapping features which complicate clinical and research …

Dementia risk genes engage gene networks poised to tune the immune response towards chronic inflammatory states

J Rexach, V Swarup, T Chang, D Geschwind - bioRxiv, 2019 - biorxiv.org
An emerging challenge in neurodegenerative dementia is understanding how immune-
associated genes and pathways contribute to disease. To achieve a refined view of …