Introduction: Numerous studies have demonstrated that abnormal levels of cholesterol are
associated with a high attributable risk for the occurrence of cardiovascular disease (CVD) …

While risk scores are invaluable tools for adapted preventive strategies, a significant gap
exists between predicted and actual event rates. Additional tools to further stratify the risk of …

Background: Emerging evidence suggests that elevated circulating levels of HDL-C (high-
density lipoprotein cholesterol) could be linked to an increased mortality risk. However, to …

Background: The prognostic importance of high-density lipoprotein cholesterol (HDL-C) as a
specific risk factor for cardiovascular (CV) disease has been challenged by recent clinical …

Background While several lines of evidence prove that elevated concentrations of low-
density lipoproteins (LDL) causally contribute to the development of atherosclerosis and its …

Abstract Aim High-density lipoproteins (HDLs) have several potentially protective vascular
effects. Most clinical studies of therapies targeting HDL have failed to show benefits vs …

Objective The association between high-density lipoprotein cholesterol (HDL-C) levels and
mortality remains controversial. We aimed to investigate the potential dose–response …

The specific interest concerning HDL cholesterol (HDL-C) is related to its ability to uptake
and return surplus cholesterol from peripheral tissues back to the liver and, therefore, to its …

Cardiovascular diseases predominantly result from atherosclerosis, a natural biological
phenomenon reflecting food intake and energy production in humans. Lipolysis of plasma …

Background Atherogenic index of plasma (AIP) has been confirmed as a novel marker for
myocardial infarction (MI), but few evidence on the long-term AIP and MI risk in general …