An insight into novel therapeutic potentials of taxifolin

Y Liu, X Shi, Y Tian, S Zhai, Y Liu, Z Xiong… - Frontiers in …, 2023 - frontiersin.org
Taxifolin is a flavonoid compound, originally isolated from the bark of Douglas fir trees,
which is often found in foods such as onions and olive oil, and is also used in commercial …

Dual role of Nrf2 in cancer: Molecular mechanisms, cellular functions and therapeutic interventions

M Poornashree, H Kumar, R Ajmeer, R Jain… - Molecular Biology …, 2023 - Springer
Background Nrf2 regulates oxidative stress, which is essential for cellular function.
Fundamental initiation of Nrf2 in many malignancies increases prosurvival genes & …

Taxifolin inhibits breast cancer cells proliferation, migration and invasion by promoting mesenchymal to epithelial transition via β-catenin signaling

J Li, L Hu, T Zhou, X Gong, R Jiang, H Li, G Kuang… - Life sciences, 2019 - Elsevier
Aim To investigate the effects and underlying mechanisms of taxifolin on proliferation,
migration and invasion of highly aggressive breast cancer in vitro and in vivo. Main methods …

Thunbergia mysorensis mediated nano silver oxide for enhanced antibacterial, antioxidant, anticancer potential and in vitro hemolysis evaluation

NR Kokila, B Mahesh, KP Roopa, BD Prasad… - Journal of Molecular …, 2022 - Elsevier
Practicing the aqueous Thunbergia mysorensis stem and flower essences for obtaining the
silver oxide nanoparticles (Ag 2 Osingle bondNPs) advances over chemical and physical …

In memory of Prof. Venkataraman: Recent advances in the synthetic methodologies of flavones

R Kshatriya, VP Jejurkar, S Saha - Tetrahedron, 2018 - Elsevier
Flavones are present in a variety of medicines and natural products and are important
structural motif due to their unique mode of physiological action. Hence the structural …

Current research on anti-breast cancer synthetic compounds

J Liu, B Ming, GH Gong, D Wang, GL Bao, LJ Yu - RSC advances, 2018 - pubs.rsc.org
Breast cancer (BC) is the most common cancer for females and its incidence tends to
increase year by year. Currently, the backbone of therapy for BC is mainly chemotherapy …

Quinoxaline-PABA bipartite hybrid derivatization approach: Design and search for antimicrobial agents

HM Patel, V Bhardwaj, P Sharma, MN Noolvi… - Journal of Molecular …, 2019 - Elsevier
In an attempt to find a new class of antimicrobial agents, in the present study we report the
synthesis of bipartite hybrid styryl derivatives of quinoxaline containing para-aminobenzoic …

Design and synthesis of quinazolinones as EGFR inhibitors to overcome EGFR resistance obstacle

HM Patel, R Pawara, A Ansari, M Noolvi… - Bioorganic & medicinal …, 2017 - Elsevier
The epidermal growth factor receptor (EGFR) T790M mutant is found in about 50% of
clinically acquired resistance to gefitinib among patients with non-small cell lung cancer …

Formal Carbene Insertion into C−O or C−N Bond: An Efficient Strategy for the Synthesis of 2‐Substituted 2H‐Chromene Derivatives from Chromene Acetals or …

D Zhang, W Hu - Advanced Synthesis & Catalysis, 2018 - Wiley Online Library
We report the palladium/Brønsted acid co‐catalyzed formal insertion of carbene into the C−
O or C− N bond of 2H‐chromene acetals or hemiaminal ethers. This transformation was …

[HTML][HTML] 2-(phenyl)-4H-chromen-4-ones: green synthesis, characterization, in vitro antifungal evaluation and molecular docking approach toward Aspergillus …

AP Devi, N Dhingra, U Bhardwaj… - Current Research in …, 2022 - Elsevier
An effective and greener method for the synthesis of 2-(phenyl)-4H-chromen-4-ones has
been developed by reacting 2-hydroxychalcones and tert-butyl hydroperoxide (TBHP) in the …