Background: Hepatoblastoma screening in the Beckwith–Wiedemann spectrum (BWSp) is
currently based on measuring a specific serum marker alpha-fetoprotein (αFP) every three …

Zusammenfassung Klinisches/methodisches Problem: Das Beckwith-Wiedemann-Spektrum
(BWSp) und die WT1-vermittelten Syndrome, Denys-Drash-Syndrom (DDS) und WAGR …

Introducción: Las alteraciones epigenéticas y genómicas de la región improntada 11p15. 5
producen crecimiento excesivo o deficiente, que se manifiesta como síndrome de Beckwith …

Background Children with overgrowth syndromes including isolated hemihyperplasia have
an increased risk for developing embryonal tumors, particularly Wilms' tumor and …

Beckwith-Wiedemann syndrome, characterized by the triad of omphalocele, macroglossia,
and gigantism, has a population incidence estimated at 1/13,700. This is likely an …

Background Extremely low‐birthweight infants (ELBWI) are at greater risk of developing
hepatoblastoma than are normal‐weight infants. Serum α‐fetoprotein (AFP) plays an …

Wilms tumor (WT), or nephroblastoma, is the most common primary malignant renal tumor of
childhood. It is the second most common solid organ abdominal tumor encountered in …

Familial adenomatous polyposis (FAP) is one of the known genetic predispositions for
colorectal cancer (CRC)[1], that is characterized by the development of numerous polyps in …

Abstract Beckwith-Wiedemann syndrome (BWS; OMIM 130650) is a heterogeneous
overgrowth syndrome characterized by visceromegaly, macroglossia, tumor predisposition …

Hepatoblastoma (HBL) stands as the primary liver tumor most frequently encountered in
children, typically identified within the initial 5 years of life. Cases involving patients older …