[HTML][HTML] Lactoferrin's anti-cancer properties: Safety, selectivity, and wide range of action

A Cutone, L Rosa, G Ianiro, MS Lepanto… - Biomolecules, 2020 - mdpi.com
Despite recent advances in cancer therapy, current treatments, including radiotherapy,
chemotherapy, and immunotherapy, although beneficial, present attendant side effects and …

Roles of the microbiota of the female reproductive tract in gynecological and reproductive health

B Zhu, Z Tao, L Edupuganti, MG Serrano… - … and Molecular Biology …, 2022 - Am Soc Microbiol
The microbiome of the female reproductive tract defies the convention that high biodiversity
is a hallmark of an optimal ecosystem. Although not universally true, a homogeneous …

[HTML][HTML] The biology of lactoferrin, an iron-binding protein that can help defend against viruses and bacteria

DB Kell, EL Heyden, E Pretorius - Frontiers in immunology, 2020 - frontiersin.org
Lactoferrin is a nutrient classically found in mammalian milk. It binds iron and is transferred
via a variety of receptors into and between cells, serum, bile, and cerebrospinal fluid. It has …

[HTML][HTML] The cervicovaginal mucus barrier

G Lacroix, V Gouyer, F Gottrand… - International journal of …, 2020 - mdpi.com
Preterm births are a global health priority that affects 15 million babies every year worldwide.
There are no effective prognostic and therapeutic strategies relating to preterm delivery, but …

[HTML][HTML] The role of genital tract microbiome in fertility: a systematic review

SG Vitale, F Ferrari, M Ciebiera, M Zgliczyńska… - International journal of …, 2021 - mdpi.com
The human microbiome plays a crucial role in determining the health status of every human
being, and the microbiome of the genital tract can affect the fertility potential before and …

[HTML][HTML] Dietary α-Linolenic acid-rich flaxseed oil exerts beneficial effects on polycystic ovary syndrome through sex steroid hormones—microbiota—inflammation axis …

T Wang, L Sha, Y Li, L Zhu, Z Wang, K Li… - Frontiers in …, 2020 - frontiersin.org
Polycystic ovary syndrome (PCOS) represents a common endocrine—metabolic disorder
disease with chronic low-grade inflammation and alteration of intestinal flora. Serving as …

[HTML][HTML] Lactoferrin in aseptic and septic inflammation

MS Lepanto, L Rosa, R Paesano, P Valenti, A Cutone - Molecules, 2019 - mdpi.com
Lactoferrin (Lf), a cationic glycoprotein able to chelate two ferric irons per molecule, is
synthesized by exocrine glands and neutrophils. Since the first anti-microbial function …

Microbiome and cervical cancer

CP Castanheira, ML Sallas, RAL Nunes, NPC Lorenzi… - Pathobiology, 2021 - karger.com
Persistent infection with some types of mucosal human papillomavirus (HPV) is the
etiological factor for the development of cervical cancer and its precursor lesions. Besides …

[HTML][HTML] Finding a balance in the vaginal microbiome: how do we treat and prevent the occurrence of bacterial vaginosis?

RJ Joseph, HL Ser, YH Kuai, LTH Tan, VJT Arasoo… - Antibiotics, 2021 - mdpi.com
Bacterial vaginosis (BV) has been reported in one-third of women worldwide at different life
stages, due to the complex balance in the ecology of the vaginal microbiota. It is a common …

[HTML][HTML] From microbiome to inflammation: the key drivers of cervical cancer

ZW Zhou, HZ Long, Y Cheng, HY Luo… - Frontiers in …, 2021 - frontiersin.org
Cervical cancer is the third leading cause of cancer-related death worldwide. Microbes and
hosts form a mutually beneficial symbiosis relationship, and various parts of the host body …