Metabolic syndrome impairs 3D mitochondrial structure, dynamics, and function in swine mesenchymal stem cells

RA Farahani, MC Farah, XY Zhu, H Tang… - Stem Cell Reviews and …, 2020 - Springer
Transplantation of autologous mesenchymal stem cells (MSCs) is an effective therapy for
several diseases. Mitochondria modulate several important aspects of MSC function, but …

Effects of mesenchymal stem cells in renovascular disease of preclinical and clinical studies: a systematic review and meta-analysis

HS Wang, MY Yi, X Wu, Q Liu, YH Deng, T Wu… - Scientific Reports, 2022 - nature.com
Renal artery stenosis (RAS) causes severe renovascular hypertension, worsening kidney
function, and increased cardiovascular morbidity. According to recent studies, mesenchymal …

Allogeneic adipose tissue‐derived stem cells ELIXCYTE® in chronic kidney disease: A phase I study assessing safety and clinical feasibility

CM Zheng, IJ Chiu, YW Chen, YH Hsu… - Journal of Cellular …, 2022 - Wiley Online Library
The purpose of this phase I clinical trial is to assess the safety and tolerability of allogeneic
adipose tissue‐derived stem cells (ADSCs) among chronic kidney disease (CKD) patients …

Autologous Extracellular Vesicles Attenuate Cardiac Injury in Experimental Atherosclerotic Renovascular Disease More Effectively Than Their Parent Mesenchymal …

S Hong, XY Zhu, Y Jiang, L Zhang, H Tang… - Stem cell reviews and …, 2023 - Springer
Atherosclerotic renovascular disease (RVD) leads to hypertension, chronic kidney disease
(CKD), and heart disease. Intrarenal delivery of mesenchymal stem cells (MSCs) and MSC …

Renovascular Disease and Mitochondrial Dysfunction in Human Mesenchymal Stem Cells

A Eirin, S Siddiqi, AG Hughes, Y Jiang… - Journal of the …, 2024 - journals.lww.com
Background: Renovascular disease leads to renal ischemia, hypertension, and eventual
kidney failure. Autologous transplantation of adipose tissue-derived mesenchymal …

Diagnosis and treatment of glomerular diseases in elderly patients

Q Qian, SH Nasr - Advances in chronic kidney disease, 2014 - Elsevier
Glomerular diseases are common in elderly patients and are a major cause of kidney failure.
Most glomerular diseases in the elderly are caused by chronic systemic diseases, including …

Novel therapeutic strategies for renovascular disease

A Eirin, SC Textor, LO Lerman - Current opinion in nephrology …, 2019 - journals.lww.com
Experimental studies and pilot clinical trials suggest that therapies targeting renal
inflammation, microvascular remodeling, and mitochondrial damage have the potential to …

Gained in translation: protective paradigms for the poststenotic kidney

LO Lerman, SC Textor - Hypertension, 2015 - Am Heart Assoc
The contribution of hypoxia to poststenotic kidney injury has been controversial, partly
because early measurements of renal-vein oxygen pressure failed to identify a fall in PO2 …

Allogeneic Cell Combination Therapy Ameliorates Chronic Kidney Disease-Induced Heart Failure with Preserved Ejection Fraction

AC Rieger, BA Tompkins, M Natsumeda… - Stem cells …, 2022 - academic.oup.com
Background Left ventricular hypertrophy and heart failure with preserved ejection fraction
(HFpEF) are primary manifestations of the cardiorenal syndrome in patients with chronic …

Рентгенохирургические методики в диагностике и лечении артериальной гипертензии

ГГ Хубулава, КЛ Козлов, АН Шишкевич… - Вестник Российской …, 2017 - elibrary.ru
Рассматриваются рентгенохирургические методики, используемые для диагностики и
лечения артериальной гипертензии. Рентгенохирургические методики позволяют …