The p7 protein is a small ion-channel-forming membrane polypeptide encoded by the
hepatitis C virus which consists of two transmembrane α-helices, TM1 and TM2, and can be …

The hepatitis C virus (HCV) p7 ion channel plays a critical role during infectious virus
production and represents an important new therapeutic target. Its activity is blocked by …

The hepatitis C virus (HCV) p7 protein forms an amantadine-sensitive ion channel required
for viral replication in chimpanzees, though its precise role in the life cycle of HCV is …

Hepatitis C virus (HCV) is a major global health burden with 2–3% of the world׳ s population
being chronically infected. Persistent infection can lead to cirrhosis and hepatocellular …

The hepatitis C virus genome encodes a polyprotein precursor that is co-and post-
translationally processed by cellular and viral proteases to yield 10 mature protein products …

Chemotherapy for patients chronically infected with hepatitis C virus (HCV) is ineffective in
over 50% of cases, generating a high demand for new drug targets. The p7 protein of HCV …

The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), has prompted an urgent need to identify effective medicines for the …

Hepatitis C virus (HCV) chronically infects 170 million individuals, causing severe liver
disease. Although antiviral chemotherapy exists, the current regimen is ineffective in 50% of …

The hepatitis C virus (HCV), a hepatotropic plus-strand RNA virus of the family Flaviviridae,
encodes a set of 10 viral proteins. These viral factors act in concert with host proteins to …

Hepatitis C virus (HCV) p7 is an integral membrane protein that forms ion channels in vitro
and that is crucial for the efficient assembly and release of infectious virions. Due to these …