The arachidonic acid (AA) pathway plays a key role in cardiovascular biology,
carcinogenesis, and many inflammatory diseases, such as asthma, arthritis, etc. Esterified …

Cytokine dysregulation is believed to play a key role in the remodeling of the immune
system at older age, with evidence pointing to an inability to fine-control systemic …

The inflammatory response is a crucial aspect of the tissues' responses to deleterious
inflammogens. This complex response involves leukocytes cells such as macrophages …

Mucosal healing plays a critical role in combatting the effects of inflammatory bowel disease,
fistulae and ulcers. While most treatments for such diseases focus on systemically delivered …

Many human diseases, including metabolic, immune and central nervous system disorders,
as well as cancer, are the consequence of an alteration in lipid metabolic enzymes and their …

In the present study, the therapeutic effects of crude anthocyanins (ACN) from the fruits of
Lycium ruthenicum Murray and the main monomer of ACN, petunidin 3-O-[rhamnopyranosyl …

The accumulation of genetic alterations in driver genes is responsible for the development
and malignant progression of colorectal cancer. Comprehensive genome analyses have …

Colorectal cancer is the second-leading cause of cancer-related deaths in the United States
and fourth-leading cause of cancer-related deaths worldwide. While cancer is largely …

Aspirin (acetylsalicylic acid) has become one of the most commonly used drugs, given its
role as an analgesic, antipyretic and agent for cardiovascular prophylaxis. Several decades …

The group IV phospholipase A 2 (PLA 2) family is comprised of six intracellular enzymes
(GIVA,-B,-C,-D,-E, and-F) commonly referred to as cytosolic PLA 2 (cPLA 2) α,-β,-γ,-δ,-ε, and …