Candida glabrata is a yeast of increasing medical relevance, particularly in critically ill
patients. It is the second most isolated Candida species associated with invasive candidiasis …

The increasing incidence and changing epidemiology of invasive fungal infections continue
to present many challenges to their effective management. The repertoire of antifungal drugs …

The membrane-integrated synthase FKS is involved in the biosynthesis of β-1, 3-glucan, the
core component of the fungal cell wall,. FKS is the target of widely prescribed antifungal …

Invasive fungal infections are an important infection concern for patients with underlying
immunosuppression. Antifungal therapy is a critical component of patient care, but …

The fungal pathogen Candida glabrata has emerged as a major health threat since it readily
acquires resistance to multiple drug classes, including triazoles and/or echinocandins. Thus …

The available antifungal armamentarium consists of only a few drug classes, many limited in
their use by significant toxicities and dangerous drug interactions. Rising opportunistic …

Fungal infections are rising all over the world every year. There are only five medical
compound classes for treatment: triazoles, echinocandins, polyenes, flucytosine and …

Background Rezafungin is a novel echinocandin with excellent activity against common
Candida species; however, limited data are available regarding rare Candida species …

In the Asia-Pacific region, Candida albicans is the predominant Candida species causing
invasive candidiasis/candidemia in Australia, Japan, Korea, Hong Kong, Malaysia …

Candida auris is an emerging and frequently multidrug-resistant pathogen against which the
echinocandins are the preferred therapeutic option. We compared killing activities of …