[HTML][HTML] Antifungal drug-resistance mechanisms in Candida biofilms
Highlights•Few classes of antifungal drugs currently exist to treat fungal infections.•Infections
caused by Candida biofilms can be resistant to known antifungal drugs.•Growth in the …
caused by Candida biofilms can be resistant to known antifungal drugs.•Growth in the …
[HTML][HTML] Prevalence of biofilms in Candida spp. bloodstream infections: A meta-analysis
MB Atiencia-Carrera, FS Cabezas-Mera, E Tejera… - PLoS …, 2022 - journals.plos.org
Context Candida-related infections are nowadays a serious Public Health Problem
emerging multidrug-resistant strains. Candida biofilm also leads bloodstream infections to …
emerging multidrug-resistant strains. Candida biofilm also leads bloodstream infections to …
[HTML][HTML] Exploring the antimicrobial, antioxidant, anticancer, biocompatibility, and larvicidal activities of selenium nanoparticles fabricated by endophytic fungal strain …
ARA Nassar, AM Eid, HM Atta, WS El Naghy… - Scientific Reports, 2023 - nature.com
Herein, four endophytic fungal strains living in healthy roots of garlic were used to produce
selenium nanoparticles (Se-NPs) via green synthesis. Penicillium verhagenii was found to …
selenium nanoparticles (Se-NPs) via green synthesis. Penicillium verhagenii was found to …
[HTML][HTML] Reviving the interest in the versatile drug nystatin: A multitude of strategies to increase its potential as an effective and safe antifungal agent
F Sousa, C Nascimento, D Ferreira, S Reis… - Advanced Drug Delivery …, 2023 - Elsevier
Nystatin is an antifungal molecule with a remarkable yet squandered versatility. In this
review, its mechanism of action is explored, along with its extensive action spectrum and …
review, its mechanism of action is explored, along with its extensive action spectrum and …
Mechanism of Candida pathogenesis: revisiting the vital drivers
Candida is the most implicated fungal pathogen in the clinical setting. Several factors play
important roles in the pathogenesis of Candida spp. Multiple transcriptional circuits …
important roles in the pathogenesis of Candida spp. Multiple transcriptional circuits …
[PDF][PDF] Bacterial pulmonary superinfections are associated with longer duration of ventilation in critically ill COVID-19 patients
The impact of secondary bacterial infections (superinfections) in coronavirus disease 2019
(COVID-19) is not well understood. In this prospective, monocentric cohort study, we aim to …
(COVID-19) is not well understood. In this prospective, monocentric cohort study, we aim to …
[HTML][HTML] Natural products and their semi-synthetic derivatives against antimicrobial-resistant human pathogenic bacteria and fungi
Human infectious diseases caused by various microbial pathogens, in general, impact a
large population of individuals every year. These microbial diseases that spread quickly …
large population of individuals every year. These microbial diseases that spread quickly …
[HTML][HTML] Antifungals and drug resistance
Definition Antifungal drugs prevent topical or invasive fungal infections (mycoses) either by
stopping growth of fungi (termed fungistatic) or by killing the fungal cells (termed fungicidal) …
stopping growth of fungi (termed fungistatic) or by killing the fungal cells (termed fungicidal) …
[HTML][HTML] Nine things genomics can tell us about Candida auris
Candida auris is a recently emerged multidrug-resistant fungal pathogen causing severe
illness in hospitalized patients. C. auris is most closely related to a few environmental or …
illness in hospitalized patients. C. auris is most closely related to a few environmental or …
[HTML][HTML] Global Prevalence of Antifungal-Resistant Candida parapsilosis: A Systematic Review and Meta-Analysis
A reliable estimate of Candida parapsilosis antifungal susceptibility in candidemia patients
is increasingly important to track the spread of C. parapsilosis bloodstream infections and …
is increasingly important to track the spread of C. parapsilosis bloodstream infections and …