Solid-state NMR investigations of extracellular matrixes and cell walls of algae, bacteria, fungi, and plants

N Ghassemi, A Poulhazan, F Deligey… - Chemical …, 2021 - ACS Publications
Extracellular matrixes (ECMs), such as the cell walls and biofilms, are important for
supporting cell integrity and function and regulating intercellular communication. These …

Fungal melanin: what do we know about structure?

JD Nosanchuk, RE Stark, A Casadevall - Frontiers in microbiology, 2015 - frontiersin.org
The production of melanin significantly enhances the virulence of many important human
pathogenic fungi. Despite fungal melanin's importance in human disease, as well as …

A molecular vision of fungal cell wall organization by functional genomics and solid-state NMR

A Chakraborty, LD Fernando, W Fang… - Nature …, 2021 - nature.com
Vast efforts have been devoted to the development of antifungal drugs targeting the cell wall,
but the supramolecular architecture of this carbohydrate-rich composite remains …

Molecular architecture of fungal cell walls revealed by solid-state NMR

X Kang, A Kirui, A Muszyński, MCD Widanage… - Nature …, 2018 - nature.com
The high mortality of invasive fungal infections, and the limited number and inefficacy of
antifungals necessitate the development of new agents with novel mechanisms and targets …

Functions of fungal melanin beyond virulence

RJB Cordero, A Casadevall - Fungal Biology Reviews, 2017 - Elsevier
Melanins are ancient biological pigments found in all kingdoms of life. In fungi, their role in
microbial pathogenesis is well established; however, these complex biomolecules also …

The viscoelastic properties of the fungal cell wall allow traffic of AmBisome as intact liposome vesicles

L Walker, P Sood, MD Lenardon, G Milne, J Olson… - MBio, 2018 - Am Soc Microbiol
The fungal cell wall is a critically important structure that represents a permeability barrier
and protective shield. We probed Candida albicans and Cryptococcus neoformans with …

Solid-state NMR of plant and fungal cell walls: a critical review

W Zhao, LD Fernando, A Kirui, F Deligey… - Solid state nuclear …, 2020 - Elsevier
The cell walls of plants and microbes are a central source for bio-renewable energy and the
major targets of antibiotics and antifungal agents. It is highly challenging to determine the …

Allomelanin: A biopolymer of intrinsic microporosity

NC McCallum, FA Son, TD Clemons… - Journal of the …, 2021 - ACS Publications
Melanin is a ubiquitous natural pigment found in a diverse array of organisms. Allomelanin
is a class of nitrogen-free melanin often found in fungi. Herein, we find artificial allomelanin …

The structural unit of melanin in the cell wall of the fungal pathogen Cryptococcus neoformans

E Camacho, R Vij, C Chrissian… - Journal of Biological …, 2019 - ASBMB
Melanins are synthesized macromolecules that are found in all biological kingdoms. These
pigments have a myriad of roles that range from microbial virulence to key components of …

Isolation and characterization of allomelanin from pathogenic black knot fungus─ a sustainable source of melanin

S Singla, KZ Htut, R Zhu, A Davis, J Ma, QZ Ni… - ACS …, 2021 - ACS Publications
Melanin, a widespread pigment found in many taxa, is widely recognized for its high
refractive index, ultraviolet (UV) protection, radical quenching ability, metal binding, and …