Peripheral nerve repair and regeneration remains among the greatest challenges in tissue
engineering and regenerative medicine. Even though peripheral nerve injuries (PNIs) are …

Peripheral nerve injury is a common clinical entity, which may arise due to traumatic,
tumorous, or even iatrogenic injury in craniomaxillofacial surgery. Despite advances in …

With significant advances in the research and application of nerve conduits, they have been
used to repair peripheral nerve injury for several decades. Nerve conduits range from …

Background Peripheral nerve damage resulting in pain, loss of sensation, or motor function
may necessitate a reconstruction with a bridging material. The RANGER® Registry was …

The MAPK/ERK pathway has a critical role in PNS development. It is required for Schwann
cell (SC) differentiation and myelination; sustained embryonic MAPK/ERK activation in SCs …

Peripheral nerve injuries can be extremely debilitating, resulting in sensory and motor loss-
of-function. Endogenous repair is limited to non-severe injuries in which transection of …

As a result of its proximity to the humeral shaft, as well as its long and tortuous course, the
radial nerve is the most frequently injured major nerve in the upper limb, with its close …

Peripheral nerve regeneration after severe traumatic nerve injury is a relevant clinical
problem. Several different strategies have been investigated to solve the problem of bridging …

Introduction Rat sciatic nerve injury (PNR) is the most utilized model in studies on peripheral
nerve regeneration. However, large animal models are increasingly favored based on the …

Nerve regeneration is a key biological process in those recovering from neural trauma. From
animal models it is known that the regenerative capacity of the peripheral nervous system …