[HTML][HTML] Conazoles

J Heeres, L Meerpoel, P Lewi - Molecules, 2010 - mdpi.com
This review provides a historical overview of the analog based drug discovery of miconazole
and its congeners, and is focused on marketed azole antifungals bearing the generic suffix …

Antifungal agents of use in animal health–chemical, biochemical and pharmacological aspects

HV Bossche, M Engelen… - Journal of veterinary …, 2003 - Wiley Online Library
A limited number of antifungal agents is licensed for use in animals, however, many of those
available for the treatment of mycoses in humans are used by veterinary practitioners. This …

Fungicidal activity of thymol and carvacrol by disrupting ergosterol biosynthesis and membrane integrity against Candida

A Ahmad, A Khan, F Akhtar, S Yousuf, I Xess… - European journal of …, 2011 - Springer
Natural isopropyl cresols have been reported to have antifungal activity. This work is an
attempt to examine thymol and carvacrol against 111 fluconazole-sensitive and-resistant …

The ATP Binding Cassette Transporter GeneCgCDR1 from Candida glabrata Is Involved in the Resistance of Clinical Isolates to Azole Antifungal Agents

D Sanglard, F Ischer, D Calabrese… - Antimicrobial agents …, 1999 - Am Soc Microbiol
The resistance mechanisms to azole antifungal agents were investigated in this study with
two pairs of Candida glabrata clinical isolates recovered from two separate AIDS patients …

Ergosterol Biosynthesis Inhibitors Become Fungicidal when Combined with Calcineurin Inhibitors against Candida albicans, Candida glabrata, and Candida krusei

C Onyewu, JR Blankenship, M Del Poeta… - Antimicrobial agents …, 2003 - Am Soc Microbiol
Azoles target the ergosterol biosynthetic enzyme lanosterol 14α-demethylase and are a
widely applied class of antifungal agents because of their broad therapeutic window, wide …

Evolution of ergosterol biosynthesis inhibitors as fungicidal against Candida

A Ahmad, A Khan, N Manzoor, LA Khan - Microbial pathogenesis, 2010 - Elsevier
Azoles target the ergosterol synthesizing enzyme lanosterol 14α-demethylase and are a
widely applied class of antifungal agents. Unfortunately azoles are generally fungistatic, and …

High prevalence of non-albicans yeasts and detection of anti-fungal resistance in the oral flora of patients with advanced cancer

J Bagg, MP Sweeney, MAO Lewis… - Palliative …, 2003 - journals.sagepub.com
Oral fungal infections frequently develop in individuals with advanced cancer. This study
examined the oral mycological flora of 207 patients receiving palliative care for advanced …

Chemical composition, antifungal and antioxidant activities of wild and cultivated Origanum compactum essential oils from the municipality of Chaoun, Morocco

L Jeldi, KO Taarabt, MA Mazri, L Ouahmane… - South African Journal of …, 2022 - Elsevier
Origanum compactum is a medicinal species endemic to Morocco and highly exploited for
its therapeutic properties. In the present study, we examined the chemical composition and …

Antifungal activity of Coriaria nepalensis essential oil by disrupting ergosterol biosynthesis and membrane integrity against Candida

A Ahmad, A Khan, P Kumar, RP Bhatt, N Manzoor - Yeast, 2011 - Wiley Online Library
Fungal diseases in humans have increased significantly with the advent of an expanding
population of immunosuppressed patients and with the introduction of sophisticated life …

Prevalence of Vaginal Colonization by Drug-Resistant Candida Species in College-Age Women with Previous Exposure to Over-the-Counter Azole Antifungals

B Mathema, E Cross, E Dun, S Park… - Clinical Infectious …, 2001 - academic.oup.com
We enrolled 382 college-age women in a cross-sectional survey to investigate the
relationship between use of over-the-counter (OTC) azole-based antifungal drugs and …