Combining transcriptomic analysis and network pharmacology to explore the mechanism by which Shaofu Zhuyu decoction improves diabetes mellitus erectile …

Y Mao, J Sun, Z Wang, Y Liu, J Sun, Z Wei, M Wang… - Phytomedicine, 2023 - Elsevier
Background Erectile dysfunction is common among the complications of diabetes mellitus.
Shaofu Zhuyu decoction (SFZYD) is commonly used to treat diabetic mellitus erectile …

[HTML][HTML] Vasorelaxant effects of biochemical constituents of various medicinal plants and their benefits in diabetes

S Demirel - World Journal of Diabetes, 2024 - ncbi.nlm.nih.gov
Endothelial function plays a pivotal role in cardiovascular health, and dysfunction in this
context diminishes vasorelaxation concomitant with endothelial activity. The nitric oxide …

[HTML][HTML] Exploring the mechanism of chuanxiong rhizoma against thrombosis based on network pharmacology, molecular docking and experimental verification

S He, X He, S Pan, W Jiang - Molecules, 2023 - mdpi.com
Chuanxiong rhizoma (CX) has been utilized for centuries as a traditional herb to treat blood
stasis syndromes. However, the pharmacological mechanisms are still not completely …

N-acetyldopamine oligomers from Periplaneta americana with anti-inflammatory and vasorelaxant effects and their spatial distribution visualized by mass spectrometry …

J Zhang, F Dong, Y Wang, C Wang, C Zhang… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Periplaneta americana is a medicinal insect that has been
applied to promote blood circulation and remove blood stasis based on traditional Chinese …

[HTML][HTML] New Bisabolane-Type Sesquiterpenoids from Curcuma longa and Their Anti-Atherosclerotic Activity

YQ Guo, GX Wu, C Peng, YQ Fan, L Li, F Liu, L Xiong - Molecules, 2023 - mdpi.com
To explore the sesquiterpenoids in Curcuma longa L. and their activity related to anti-
atherosclerosis. The chemical compounds of the rhizomes of C. longa were separated and …

[HTML][HTML] A pair of new enantiomeric hybrid phthalide–adenines with a rare 5-oxa-1-azaspiro [3, 4] octane moiety and two pairs of new enantiomeric hybrid paraethyl …

R Feng, J Liu, L Guo, HZ Shu, QM Zhou, L Liu… - Arabian Journal of …, 2023 - Elsevier
Three pairs of new enantiomeric adenine alkaloids,(+)/(−)-liguadenines A–C [(+)/(−)-1–3],
were isolated from the rhizome of Ligusticum chuanxiong Hort. The structures and absolute …

[HTML][HTML] Mechanism of Danggui Buxue decoction in the treatment of myocardial infarction based on network pharmacology and experimental identification

C Shen, Q Chen, S Chen, Y Lin - Heliyon, 2024 - cell.com
Background Myocardial infarction (MI) remains one of the major causes of high morbidity
and mortality worldwide. Danggui Buxue Decoction (DBD)—an ancient Chinese herbal …

[HTML][HTML] Network pharmacology-based and experimental identification of the effects of Renshen Yangrong decoction on myocardial infarction

J Zhao, X Xu, X Yang - Frontiers in Pharmacology, 2022 - frontiersin.org
Objective: Myocardial infarction (MI) is one of the leading causes of death worldwide.
Currently, the drugs used to treat MI have various side effects. Emerging evidence supports …

[HTML][HTML] Detoxification and Activating Blood Circulation Decoction Promotes Reendothelialization of Damaged Blood Vessels via VEGF Signaling Pathway Activation …

Z Liu, G Xie, Z Li, H Luo, J Zhou, J Cheng… - Biological and …, 2024 - jstage.jst.go.jp
The occurrence of in-stent restenosis (ISR) poses a significant challenge for percutaneous
coronary intervention (PCI). Thus, the promotion of vascular reendothelialization is essential …

[HTML][HTML] Curcumanes E and F, two rare sesquiterpenoids with a dicyclo[3.3.1]nonane moiety, from Curcuma longa and their vasorelaxant activities

J Liu, MM Qiao, C Peng, HZ Shu, CW Meng… - Frontiers in …, 2022 - frontiersin.org
Two new sesquiterpenoids, curcumanes E (1) and F (2), were isolated from the rhizome of
Curcuma longa, and their structures and absolute configurations were examined using …