Sex differences in energy metabolism: natural selection, mechanisms and consequences
F Mauvais-Jarvis - Nature Reviews Nephrology, 2024 - nature.com
Metabolic homeostasis operates differently in men and women. This sex asymmetry is the
result of evolutionary adaptations that enable women to resist loss of energy stores and …
result of evolutionary adaptations that enable women to resist loss of energy stores and …
[HTML][HTML] The epigenetics of animal personality
Animal personality, consistent individual differences in behaviour, is an important concept
for understanding how individuals vary in how they cope with environmental challenges. In …
for understanding how individuals vary in how they cope with environmental challenges. In …
Truncated Tau caused by intron retention is enriched in Alzheimer's disease cortex and exhibits altered biochemical properties
ZK Ngian, YY Tan, CT Choo, WQ Lin… - Proceedings of the …, 2022 - National Acad Sciences
Alzheimer's disease (AD) is characterized by the accumulation of amyloid-β plaques and
Tau tangles in brain tissues. Recent studies indicate that aberrant splicing and increased …
Tau tangles in brain tissues. Recent studies indicate that aberrant splicing and increased …
Characterisation of ethnic differences in DNA methylation between UK-resident South Asians and Europeans
HR Elliott, K Burrows, JL Min, T Tillin, D Mason… - Clinical …, 2022 - Springer
Ethnic differences in non-communicable disease risk have been described between
individuals of South Asian and European ethnicity that are only partially explained by …
individuals of South Asian and European ethnicity that are only partially explained by …
Associations between prenatal phthalate exposure and childhood epigenetic age acceleration
Background Phthalates, a group of pervasive endocrine-disrupting chemicals found in
plastics and personal care products, have been associated with a wide range of …
plastics and personal care products, have been associated with a wide range of …
Maternal adverse childhood experiences (ACEs) and DNA methylation of newborns in cord blood
P Collender, AK Bozack, S Veazie… - Clinical …, 2023 - Springer
Abstract Background Adverse childhood experiences (ACEs) increase the risk of poor health
outcomes later in life. Psychosocial stressors may also have intergenerational health effects …
outcomes later in life. Psychosocial stressors may also have intergenerational health effects …
Who's afraid of the X? Incorporating the X and Y chromosomes into the analysis of DNA methylation array data
Background Many human disease phenotypes manifest differently by sex, making the
development of methods for incorporating X and Y-chromosome data into analyses vital …
development of methods for incorporating X and Y-chromosome data into analyses vital …
PM2. 5 and constituent component impacts on global DNA methylation in patients with idiopathic pulmonary fibrosis
GC Goobie, X Li, CJ Ryerson, C Carlsten… - Environmental …, 2023 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive interstitial lung disease (ILD)
whose outcomes are worsened with air pollution exposures. DNA methylation (DNAm) …
whose outcomes are worsened with air pollution exposures. DNA methylation (DNAm) …
Gestational age acceleration is associated with epigenetic biomarkers of prenatal physiologic stress exposure
Background Physiological maternal stress response, such as imbalance in the
glucocorticoid pathway and immune system seems to be mediated by DNA methylation …
glucocorticoid pathway and immune system seems to be mediated by DNA methylation …
Sex effects on DNA methylation affect discovery in epigenome-wide association study of schizophrenia
M Tesfaye, LM Spindola, AK Stavrum, A Shadrin… - Molecular …, 2024 - nature.com
Sex differences in the epidemiology and clinical characteristics of schizophrenia are well-
known; however, the molecular mechanisms underlying these differences remain unclear …
known; however, the molecular mechanisms underlying these differences remain unclear …