Sex differences in energy metabolism: natural selection, mechanisms and consequences

F Mauvais-Jarvis - Nature Reviews Nephrology, 2024 - nature.com
Metabolic homeostasis operates differently in men and women. This sex asymmetry is the
result of evolutionary adaptations that enable women to resist loss of energy stores and …

[HTML][HTML] The epigenetics of animal personality

K van Oers, K van den Heuvel, B Sepers - Neuroscience & Biobehavioral …, 2023 - Elsevier
Animal personality, consistent individual differences in behaviour, is an important concept
for understanding how individuals vary in how they cope with environmental challenges. In …

Truncated Tau caused by intron retention is enriched in Alzheimer's disease cortex and exhibits altered biochemical properties

ZK Ngian, YY Tan, CT Choo, WQ Lin… - Proceedings of the …, 2022 - National Acad Sciences
Alzheimer's disease (AD) is characterized by the accumulation of amyloid-β plaques and
Tau tangles in brain tissues. Recent studies indicate that aberrant splicing and increased …

Characterisation of ethnic differences in DNA methylation between UK-resident South Asians and Europeans

HR Elliott, K Burrows, JL Min, T Tillin, D Mason… - Clinical …, 2022 - Springer
Ethnic differences in non-communicable disease risk have been described between
individuals of South Asian and European ethnicity that are only partially explained by …

Associations between prenatal phthalate exposure and childhood epigenetic age acceleration

D Khodasevich, N Holland, A Hubbard, K Harley… - Environmental …, 2023 - Elsevier
Background Phthalates, a group of pervasive endocrine-disrupting chemicals found in
plastics and personal care products, have been associated with a wide range of …

Maternal adverse childhood experiences (ACEs) and DNA methylation of newborns in cord blood

P Collender, AK Bozack, S Veazie… - Clinical …, 2023 - Springer
Abstract Background Adverse childhood experiences (ACEs) increase the risk of poor health
outcomes later in life. Psychosocial stressors may also have intergenerational health effects …

Who's afraid of the X? Incorporating the X and Y chromosomes into the analysis of DNA methylation array data

AM Inkster, MT Wong, AM Matthews, CJ Brown… - Epigenetics & …, 2023 - Springer
Background Many human disease phenotypes manifest differently by sex, making the
development of methods for incorporating X and Y-chromosome data into analyses vital …

PM2. 5 and constituent component impacts on global DNA methylation in patients with idiopathic pulmonary fibrosis

GC Goobie, X Li, CJ Ryerson, C Carlsten… - Environmental …, 2023 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive interstitial lung disease (ILD)
whose outcomes are worsened with air pollution exposures. DNA methylation (DNAm) …

Gestational age acceleration is associated with epigenetic biomarkers of prenatal physiologic stress exposure

V Euclydes, C Gomes, G Gouveia, VD Gastaldi… - Clinical …, 2022 - Springer
Background Physiological maternal stress response, such as imbalance in the
glucocorticoid pathway and immune system seems to be mediated by DNA methylation …

Sex effects on DNA methylation affect discovery in epigenome-wide association study of schizophrenia

M Tesfaye, LM Spindola, AK Stavrum, A Shadrin… - Molecular …, 2024 - nature.com
Sex differences in the epidemiology and clinical characteristics of schizophrenia are well-
known; however, the molecular mechanisms underlying these differences remain unclear …