Mechanical properties of extracellular matrices (ECMs) regulate essential cell behaviours,
including differentiation, migration and proliferation, through mechanotransduction. Studies …

Life emerges from thousands of biochemical processes occurring within a shared
intracellular environment. We have gained deep insights from in vitro reconstitution of …

Background Detailed information on the temperature dependence of tissue thermophysical
and mechanical properties is pivotal for the optimal implementation of mathematical models …

Peripheral nerve injury (PNI) caused by trauma, chronic disease and other factors may lead
to partial or complete loss of sensory, motor and autonomic functions, as well as neuropathic …

Novel neuroimaging techniques that can sensitivity characterize healthy brain aging and
detect subtle neuropathologies have enormous potential to assist in the early detection of …

Alzheimer's disease (AD) represents one of the most common and debilitating
neurodegenerative disorders. By the end of 2040, AD patients might reach 11.2 million in …

Both healthy and pathological brain aging are characterized by various degrees of cognitive
decline that strongly correlate with morphological changes referred to as cerebral atrophy …

The biomechanical properties of the brain microenvironment, which is composed of different
neural cell types, the extracellular matrix, and blood vessels, are critical for normal brain …

Understanding how Aβ42 oligomers induce changes in neurons from a mechanobiological
perspective has important implications in neuronal dysfunction relevant to …

The blood-brain barrier (BBB) is a semipermeable unit that serves to vascularize the central
nervous system (CNS) while tightly regulating the movement of molecules, ions, and cells …