Endocytosis is a critical step in the process by which many therapeutic nanomedicines reach
their intracellular targets. Our understanding of cellular uptake mechanisms has developed …

Endocytosis is a complex process whereby cell surface proteins, lipids and fluid from the
extracellular environment are packaged, sorted and internalized into cells. Endocytosis is …

Humans are exposed to nanoscopical nanobiovectors (eg coronavirus SARS-CoV-2) as
well as abiotic metal/carbon-based nanomaterials that enter cells serendipitously or …

Cells are constantly submitted to external mechanical stresses, which they must withstand
and respond to. By forming a physical boundary between cells and their environment that is …

Nanoparticles (NP) are attractive options for the therapeutic delivery of active
pharmaceutical drugs, proteins and nucleic acids into cells, tissues and organs. Research …

Many cellular processes rely on precise and timely deformation of the cell membrane. While
many proteins participate in membrane reshaping and scission, usually in highly specialized …

Endocytosis mediates the uptake of extracellular proteins, micronutrients and
transmembrane cell surface proteins. Importantly, many viruses, toxins and bacteria hijack …

The Arp2/3 complex orchestrates the formation of branched actin networks at the interface
between the cytoplasm and membranes. Although it is widely appreciated that these …

Many viruses utilize the host endo-lysosomal network for infection. Tracing the endocytic
itinerary of SARS-CoV-2 can provide insights into viral trafficking and aid in designing new …

Plasma membrane tension regulates many key cellular processes. It is modulated by, and
can modulate, membrane trafficking. However, the cellular pathway (s) involved in this …