The major facilitator superfamily (MFS) is the largest known superfamily of secondary active
transporters. MFS transporters are responsible for transporting a broad spectrum of …

The concentration of glucose in plasma is held within narrow limits (4–10 mmol/l), primarily
to ensure fuel supply to the brain. Kidneys play a role in glucose homeostasis in the body by …

Proton-coupled monocarboxylate transporters MCT1-4 catalyze the transmembrane
movement of metabolically essential monocarboxylates and have been targeted for cancer …

Carbohydrates comprise a large fraction of the typical diet, yet humans are only able to
directly process some types of starch and simple sugars. The remainder transits the large …

Docosahexaenoic acid is an omega-3 fatty acid that is essential for neurological
development and function, and it is supplied to the brain and eyes predominantly from …

The determination of the crystal structures of small-molecule transporters has shed light on
the conformational changes that take place during structural isomerization from outward-to …

Lignin is the most abundant phenolic polymer; thus, its decomposition by microorganisms is
fundamental to carbon cycling on earth. Lignin breakdown is initiated by depolymerization …

Fluctuations in environmental osmolarity are ubiquitous stress factors in many natural
habitats of microorganisms, as they inevitably trigger osmotically instigated fluxes of water …

Abstract The Polysaccharide Utilization Loci (PUL) database was launched in 2015 to
present PUL predictions in∼ 70 Bacteroidetes species isolated from the human …

Glucose is the primary fuel to life on earth. Cellular uptake of glucose is a fundamental
process for metabolism, growth, and homeostasis. Three families of secondary glucose …