Physiology and pathophysiology of human airway mucus
The mucus clearance system is the dominant mechanical host defense system of the human
lung. Mucus is cleared from the lung by cilia and airflow, including both two-phase gas-liquid …
lung. Mucus is cleared from the lung by cilia and airflow, including both two-phase gas-liquid …
Bronchiectasis—a clinical review
AE O'Donnell - New England Journal of Medicine, 2022 - Mass Medical Soc
Bronchiectasis — A Clinical Review | New England Journal of Medicine Skip to main content The
New England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES …
New England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES …
Bronchiectasis in Europe: data on disease characteristics from the European Bronchiectasis registry (EMBARC)
JD Chalmers, E Polverino, ML Crichton… - The Lancet …, 2023 - thelancet.com
Background Bronchiectasis is a heterogeneous, neglected disease with few multicentre
studies exploring the causes, severity, microbiology, and treatment of the disease across …
studies exploring the causes, severity, microbiology, and treatment of the disease across …
Treatable traits in the NOVELTY study
Background and objective Asthma and chronic obstructive pulmonary disease (COPD) are
two prevalent and complex diseases that require personalized management. Although a …
two prevalent and complex diseases that require personalized management. Although a …
Genome sequencing reveals underdiagnosis of primary ciliary dyskinesia in bronchiectasis
Background Bronchiectasis can result from infectious, genetic, immunological and allergic
causes. 60–80% of cases are idiopathic, but a well-recognised genetic cause is the motile …
causes. 60–80% of cases are idiopathic, but a well-recognised genetic cause is the motile …
Inhaled corticosteroids in adults with non-cystic fibrosis bronchiectasis: from bench to bedside. A narrative review
MÁ Martínez-García, G Oscullo, A García-Ortega… - Drugs, 2022 - Springer
Due to their potent anti-inflammatory capacity (particularly in predominantly eosinophilic
inflammation) and immunosuppressive properties, inhaled corticosteroids (ICSs) are widely …
inflammation) and immunosuppressive properties, inhaled corticosteroids (ICSs) are widely …
Pathophysiology and genomics of bronchiectasis
L Perea, R Faner, JD Chalmers… - European Respiratory …, 2024 - err.ersjournals.com
Bronchiectasis is a complex and heterogeneous inflammatory chronic respiratory disease
with an unknown cause in around 30–40% of patients. The presence of airway infection …
with an unknown cause in around 30–40% of patients. The presence of airway infection …
Infection and the microbiome in bronchiectasis
M Mac Aogáin, AJ Dicker, P Mertsch… - European Respiratory …, 2024 - err.ersjournals.com
Bronchiectasis is marked by bronchial dilatation, recurrent infections and significant
morbidity, underpinned by a complex interplay between microbial dysbiosis and immune …
morbidity, underpinned by a complex interplay between microbial dysbiosis and immune …
Eradication treatment for Pseudomonas aeruginosa infection in adults with bronchiectasis: a systematic review and meta-analysis
M Conceição, M Shteinberg… - European …, 2024 - Eur Respiratory Soc
Introduction: Pseudomonas aeruginosa is the most commonly isolated pathogen in
bronchiectasis and is associated with worse outcomes. Eradication treatment is …
bronchiectasis and is associated with worse outcomes. Eradication treatment is …
ROSE: radiology, obstruction, symptoms and exposure–a Delphi consensus definition of the association of COPD and bronchiectasis by the EMBARC Airways …
L Traversi, M Miravitlles, MA Martinez-Garcia… - ERJ open …, 2021 - Eur Respiratory Soc
Introduction The coexistence of COPD and bronchiectasis seems to be common and
associated with a worse prognosis than for either disease individually. However, no …
associated with a worse prognosis than for either disease individually. However, no …