Safety of dietary guanidinoacetic acid: a villain of a good guy?

SM Ostojic - Nutrients, 2021 - mdpi.com
Guanidinoacetic acid (GAA) is a natural amino acid derivative that is well-recognized for its
central role in the biosynthesis of creatine, an essential compound involved in cellular …

Tackling guanidinoacetic acid for advanced cellular bioenergetics

SM Ostojic - Nutrition, 2017 - Elsevier
Tissues with high-energy output, such as the brain and skeletal muscle, suffer the most from
impaired or depleted energy levels, with innovative nutritional approaches needed to …

Creatine monohydrate and guanidinoacetic acid supplementation affects the growth performance, meat quality, and creatine metabolism of finishing pigs

J Li, L Zhang, Y Fu, Y Li, Y Jiang… - Journal of Agricultural …, 2018 - ACS Publications
This study aimed to investigate the effects of creatine monohydrate (CMH) and
guanidinoacetic acid (GAA) supplementation on the growth performance, meat quality, and …

Guanidinoacetic acid versus creatine for improved brain and muscle creatine levels: a superiority pilot trial in healthy men

SM Ostojic, J Ostojic, P Drid… - … Physiology, Nutrition, and …, 2016 - cdnsciencepub.com
In this randomized, double-blind, crossover trial, we evaluated whether 4-week
supplementation with guanidinoacetic acid (GAA) is superior to creatine in facilitating …

Effects of methionine and guanidinoacetic acid supplementation on performance and energy metabolites in breast muscle of male broiler chickens fed corn-soybean …

M Majdeddin, A Golian, H Kermanshahi… - British poultry …, 2019 - Taylor & Francis
Guanidinoacetic acid (GAA) is the single endogenous precursor of creatine, which plays a
critical role in energy homeostasis of cells. Since GAA is endogenously converted to …

Effects of dietary guanidinoacetic acid on growth performance, guanidinoacetic acid absorption and creatine metabolism of lambs

S Zhang, C Zang, J Pan, C Ma, C Wang, X Li, W Cai… - PLoS …, 2022 - journals.plos.org
Guanidinoacetic acid (GAA) is the only precursor for the creatine synthesis of vertebrates.
Creatine (Cr) and phosphocreatine (PCr) are able to provide energy for the rapid growth and …

Dietary guanidinoacetic acid improves the growth performance and skeletal muscle development of finishing pigs through changing myogenic gene expression and …

Y Lu, T Zou, Z Wang, J Yang, L Li, X Guo… - Journal of Animal …, 2020 - Wiley Online Library
This study aimed to evaluate the effects of dietary guanidine acetic acid (GAA)
supplementation on growth performance, carcass traits and the expression of muscle growth …

[HTML][HTML] Guanidinoacetic acid as a novel food for skeletal muscle health

SM Ostojic, V Premusz, D Nagy, P Acs - Journal of Functional Foods, 2020 - Elsevier
Guanidinoacetic acid (GAA) is a direct endogenic precursor of creatine. GAA is also a re-
discovered nutraceutical that has been put forward as an energy-facilitating compound by …

Effect of dietary sulphur amino acid levels and guanidinoacetic acid supplementation on performance, carcase yield and energetic molecular metabolites in broiler …

H Zarghi, A Golian… - Italian Journal of Animal …, 2020 - Taylor & Francis
The aim of the present study was to evaluate the effects of dietary total sulphur amino acids
(TSAA) levels and guanidinoacetic acid (GAA) supplementation on performance, carcase …

Effects of guanidinoacetic acid and betaine on growth performance, energy and nitrogen metabolism, and rumen microbial protein synthesis in lambs

G Ren, X Hao, X Zhang, S Liu, J Zhang - Animal Feed Science and …, 2022 - Elsevier
In this study, we investigated the effects of guanidinoacetic acid (GAA) and betaine (BT) on
growth performance, nutrient digestion, energy-nitrogen metabolism, and microbial protein …