Mechanisms of action of non-enzymatic antioxidants to control oxidative stress during in vitro follicle growth, oocyte maturation, and embryo development

BR Silva, JRV Silva - Animal reproduction science, 2023 - Elsevier
In vitro follicle growth and oocyte maturation still has a series of limitations, since not all
oocytes matured in vitro have the potential to develop in viable embryos. One of the factors …

[HTML][HTML] Role of oxidative stress in male infertility

NB Takalani, EM Monageng, K Mohlala… - Reproduction and …, 2023 - raf.bioscientifica.com
Graphical abstract Abstract Infertility affects millions of couples worldwide. Oxidative stress
(OS) causes peroxidation of lipids and damage to spermatozoa, thus, reducing the quality of …

[HTML][HTML] Potential effects of assisted reproductive technology on telomere length and telomerase activity in human oocytes and early embryos

B Tire, S Ozturk - Journal of Ovarian Research, 2023 - Springer
Telomeres are repetitive DNA sequences at eukaryotic chromosome ends and function in
maintaining genome integrity and stability. These unique structures undergo shortening due …

Transcriptomic integrity of human oocytes used in ARTs: technical and intrinsic factor effects

B Ducreux, C Patrat, J Trasler… - Human Reproduction …, 2024 - academic.oup.com
Background Millions of children have been born throughout the world thanks to ARTs, the
harmlessness of which has not yet been fully demonstrated. For years, efforts to evaluate the …

A review of the use of antioxidants in bovine sperm preparation protocols

V Sapanidou, MP Tsantarliotou… - Animal Reproduction …, 2023 - Elsevier
Reactive oxygen species (ROS) and oxidative stress (OS), the imbalance between the
production of free radicals and the cellular antioxidant defenses, are discussed in relation to …

[HTML][HTML] Oxidative stress in assisted reproductive techniques, with a focus on an underestimated risk factor

P Mauchart, RA Vass, B Nagy, E Sulyok… - Current issues in …, 2023 - mdpi.com
Based on current findings, the presence of oxidative stress has a significant impact on the
quality of gametes and embryos when performing assisted reproductive techniques (ART) …

[HTML][HTML] DNA methylation in offspring conceived after assisted reproductive techniques: a systematic review and meta-analysis

R Cannarella, A Crafa, LM Mongioì, L Leggio… - Journal of clinical …, 2022 - mdpi.com
Background: In the last 40 years, assisted reproductive techniques (ARTs) have emerged as
potentially resolving procedures for couple infertility. This study aims to evaluate whether …

[HTML][HTML] New insight on the in vitro effects of melatonin in preserving human sperm quality

S Minucci, M Venditti - International Journal of Molecular Sciences, 2022 - mdpi.com
Spermatozoa (SPZ) are sensitive to stressful conditions, particularly oxidative stress, which
alters their quality; thus, the use of protective molecules as an antioxidant is encouraged …

Optimizing swine in vitro embryo production with growth factor and antioxidant supplementation during oocyte maturation

L Currin, WG Glanzner, K Gutierrez, MP de Macedo… - Theriogenology, 2022 - Elsevier
Porcine in vitro fertilization often results in low embryo development rates compared to other
livestock species, which is often associated with either a low fertilization rate or high …

[HTML][HTML] Human sperm as an in vitro model to assess the efficacy of antioxidant supplements during sperm handling: A narrative review

E Moretti, C Signorini, R Corsaro, M Giamalidi… - Antioxidants, 2023 - mdpi.com
Spermatozoa are highly differentiated cells that produce reactive oxygen species (ROS) due
to aerobic metabolism. Below a certain threshold, ROS are important in signal transduction …