L-Glutamic acid is the main excitatory neurotransmitter in the central nervous system (CNS).
Its associated receptors localized on neuronal and non-neuronal cells mediate rapid …

Delirium is a common, morbid, and costly syndrome that is closely linked to Alzheimer's
disease (AD) and AD‐related dementias (ADRD) as a risk factor and outcome. Human …

Background Alzheimer's disease (AD) is a prevalent neurodegenerative disorder causing
progressive dementia. Research suggests that microRNAs (miRNAs) could serve as …

Direct nose-to-brain drug delivery offers the opportunity to treat central nervous system
disorders more effectively due to the possibility of drug molecules reaching the brain without …

Alzheimer's disease (AD) is a devastating neurodegenerative disease with limited
therapeutic options. Cellular transplantation of healthy exogenic neurons to replace and …

A form of dementia distinct from healthy cognitive aging, Alzheimer's disease (AD) is a
complex multi-stage disease that currently afflicts over 50 million people worldwide …

The synthetic approaches to three new AMPA receptor modulators—derivatives of 1, 11-
dimethyl-3, 6, 9-triazatricyclo [7.3. 1.13, 11] tetradecane-4, 8, 12-trione—had been …

More than 20 years since its discovery, our understanding of Pin1 function in various
diseases continues to improve. Pin1 plays a crucial role in pathogenesis and has been …

Background Jiaohong pills (JHP) consist of Pericarpium Zanthoxyli (PZ) and Radix
Rehmanniae, two herbs that have been extensively investigated over many years due to …

Parkinson's disease (PD) is the second-most prevalent central nervous system (CNS)
neurodegenerative condition. Over the past few decades, suppression of BCR-Abelson …