Change is inevitable. In early evolution, due to the limited availability of resources, the sole
purpose of living organisms was to survive long enough to transmit their genes to the next …

Selective immunoglobulin E (IgE) deficiency (IgED) is defined as serum levels of IgE more
than or equal to 2 kIU/L and is associated with immune dysregulation and autoimmunity …

The pathophysiology of some inflammatory arterial diseases (such as vasculitis,
atherogenesis and aneurysms) has been widely investigated in the last decades. Among …

Aims Levels of circulating CD14highCD16+ monocytes increase in atherosclerotic patients
and are predictive of future cardiovascular events. Platelet activation has been identified as …

Atherosclerosis (AS), known as the chronic inflammatory disease, results from the
dysfunction of vascular endothelial cells (VECs). Transforming growth factor-β1 (TGF-β1) …

Background Immune thrombocytopenia (ITP) is an autoimmune hemorrhagic disease
characterized by low platelet count and bleeding manifestations. However, some patients …

Living on a sun-drenched planet has necessitated adaption to and protection from the
harmful effects of solar ultraviolet (UV) radiation, particularly skin cancer. However …

As the world's aging population increases, cardiovascular diseases (CVDs) associated with
aging deserve increasing attention. CVD in association with age is considered a major …

Accumulation of lipids is the central event in the development of atherosclerotic lesion.
Circulating low-density lipoprotein (LDL) particles are known to be the major source of …

One of the first manifestations of atherosclerosis is accumulation of extra-and intracellular
cholesterol esters in the arterial intima. Formation of foam cells is considered as a trigger in …