Objective (s): MicroRNAs (miRNAs) are a class of short RNAs that control the biological
processes including cell proliferation, apoptosis and development. Aberrant expression of …

The formation of blood capillaries to sustain development and growth of new tissues is
referred to as angiogenesis. Angiogenesis is pivotal in both carcinogenesis and metastasis …

Progressive up-regulation of β-catenin signaling is very common in the transformation of
colorectal epithelium to colorectal cancer (CRC). Practical measures for opposing such …

The combination of the cancer mitochondrial metabolic inhibitor CPI-613 and
hydroxychloroquine has tumor-suppressive effects on clear cell sarcoma, which shares …

A novel series of silibinin and 2, 3-dehydrosilybin derivatives bearing carbamate groups
were designed, synthesized and their in vitro anticancer activities were screened against …

Modern preparations of milk thistle have been used since 1960− 1970s. By their chemical
nature, the active substances of milk thistle are flavonoids (flavonolignans). The …

Fluorescence molecular imaging has been used to target tumors in mice with xenograft
tumors. However, tumor imaging is largely distorted by the aggregation of fluorescent probes …

Silibinin is a phyto-flavonoid compound and has been reported to exert anticancer effects on
several tumors, including breast cancer. The present study exploited Flow cytometry, H&E …

Background: Isolated adipose stem cells have been reported to encourage migration and
early metastasis of breast cancer. Mimicking a surgical situation, the authors developed a …

Despite significant technological advancements in conventional therapies, cancer remains
one of the main causes of death worldwide. Although substantial progress has been made …