The impact of interferon-regulatory factors to macrophage differentiation and polarization into M1 and M2

DA Chistiakov, VA Myasoedova, VV Revin… - Immunobiology, 2018 - Elsevier
The mononuclear phagocytes control the body homeostasis through the involvement in
resolving tissue injury and further wound healing. Indeed, local tissue microenvironmental …

Role of Th17 cells in the pathogenesis of CNS inflammatory demyelination

A Rostami, B Ciric - Journal of the neurological sciences, 2013 - Elsevier
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS). The
etiology of MS is not well understood, but it is believed that myelin-specific CD4+ T cells play …

Increasing levels of interleukin (IL)-1Ra and IL-6 during the first 2 days of hospitalization in unstable angina are associated with increased risk of in-hospital coronary …

LM Biasucci, G Liuzzo, G Fantuzzi, G Caligiuri… - Circulation, 1999 - Am Heart Assoc
Background—A growing body of evidence suggests a role for inflammation in acute
coronary syndromes. The aim of this study was to assess the role of proinflammatory …

GM-CSF in inflammation and autoimmunity

JA Hamilton - Trends in immunology, 2002 - cell.com
Granulocyte macrophage-colony stimulating factor (GM-CSF) is now best viewed as a major
regulator governing the functions of granulocyte and macrophage lineage populations at all …

Differentiation factors and cytokines in the atherosclerotic plaque micro-environment as a trigger for macrophage polarisation

IMJ Wolfs, MMPC Donners… - Thrombosis and …, 2011 - thieme-connect.com
The phenotype of macrophages in atherosclerotic lesions can vary dramatically, from a large
lipid laden foam cell to a small inflammatory cell. Classically, the concept of macrophage …

Cytokines in the pathogenesis of atherosclerosis

JL Young, P Libby, U Schönbeck - Thrombosis and …, 2002 - thieme-connect.com
Research during the last two decades established atheromatous lesions as active sites of
inflammation and immune responses, contrasting to the traditional view of atherosclerosis as …

Functions of granulocyte-macrophage colony-stimulating factor

AJ Fleetwood, AD Cook… - Critical Reviews™ in …, 2005 - dl.begellhouse.com
ABSTRACT GM-CSF was originally defined by its ability to generate in vitro granulocyte and
macrophage colonies from bone marrow precursor cells. Apart from its physiological role in …

[HTML][HTML] A review of GM-CSF therapy in sepsis

B Mathias, BE Szpila, FA Moore, PA Efron… - Medicine, 2015 - journals.lww.com
A Review of GM-CSF Therapy in Sepsis : Medicine A Review of GM-CSF Therapy in Sepsis :
Medicine Log in or Register Get new issue alertsGet alerts Secondary Logo Journal Logo …

Differentiated properties and proliferation of arterial smooth muscle cells in culture

J Thyberg - International review of cytology, 1996 - Elsevier
The smooth muscle cell is the sole cell type normally found in the media of mammalian
arteries. In the adult, it is a terminally differentiated cell that expresses cytoskeletal marker …

Cytokines and cardiovascular disease

VC Mehra, VS Ramgolam… - Journal of leukocyte …, 2005 - academic.oup.com
The role of cytokines in the pathogenesis of cardiovascular disease is increasingly evident
since the identification of immune/inflammatory mechanisms in atherosclerosis and heart …