Molecular Landscape of LncRNAs in Prostate Cancer: A focus on pathways and therapeutic targets for intervention

S Mirzaei, MDA Paskeh, E Okina, MH Gholami… - Journal of Experimental …, 2022 - Springer
Background One of the most malignant tumors in men is prostate cancer that is still incurable
due to its heterogenous and progressive natures. Genetic and epigenetic changes play …

Long non-coding RNA/epithelial-mesenchymal transition axis in human cancers: Tumorigenesis, chemoresistance, and radioresistance

M Hashemi, S Hajimazdarany, CD Mohan… - Pharmacological …, 2022 - Elsevier
Epithelial-to-mesenchymal transition (EMT) is a process that involves the transformation of
polarized epithelial cells to attain a mesenchymal phenotype that presents an elevated …

[HTML][HTML] Malignant function of nuclear factor-kappaB axis in prostate cancer: Molecular interactions and regulation by non-coding RNAs

RR Al-Rashidi, SAM Noraldeen, AK Kareem… - Pharmacological …, 2023 - Elsevier
Prostate carcinoma is a malignant situation that arises from genomic alterations in the
prostate, leading to changes in tumorigenesis. The NF-κB pathway modulates various …

lncRNA FDNCR promotes apoptosis of granulosa cells by targeting the miR-543-3p/DCN/TGF-β signaling pathway in Hu sheep

X Yao, XX Gao, Y Bao, MA El-Samahy, J Yang… - … Therapy-Nucleic Acids, 2021 - cell.com
Long non-coding RNAs (lncRNAs) regulate the development of follicles and reproductive
diseases, but the mechanisms by which lncRNAs regulate ovarian functions and fertility …

Evaluation of long non-coding RNA (LncRNA) in the pathogenesis of chemotherapy resistance in cervical cancer: diagnostic and prognostic approach

N Modabber, SS Mahboub, S Khoshravesh… - Molecular …, 2023 - Springer
Cervical cancer (CC), caused by human papillomavirus (HPV), is a leading cause of female
malignancies worldwide. Therefore, understanding the underlying mechanisms of CC …

[HTML][HTML] A review on the role of PCAT6 lncRNA in tumorigenesis

S Ghafouri-Fard, T Khoshbakht, M Taheri… - Biomedicine & …, 2021 - Elsevier
Prostate cancer-associated transcript 6 (PCAT6) is a long non-coding RNA (lncRNA) firstly
identified in 2013 through an integrative genomic analysis of different cancer tissues. This …

Knockdown of MIR4435-2HG suppresses the proliferation, migration and invasion of cervical cancer cells via regulating the miR-128-3p/MSI2 axis in vitro

R Wang, L Liu, J Jiao, D Gao - Cancer management and research, 2020 - Taylor & Francis
Purpose Long non-coding RNAs (lncRNAs) play major roles in the development of several
cancers, including cervical cancer (CC). The purpose of the present study is to explore the …

Enzalutamide-induced upregulation of PCAT6 promotes prostate cancer neuroendocrine differentiation by regulating miR-326/HNRNPA2B1 axis

B Liu, HY Jiang, T Yuan, J Luo, WD Zhou… - Frontiers in …, 2021 - frontiersin.org
Our previous studies have demonstrated that Enzalutamide-induced upregulation of long
non-coding RNA p21 (lncRNA-p21) facilitates prostate cancer (PCa) neuroendocrine …

RHO GTPase-related long noncoding RNAs in human cancers

M Saliani, A Mirzaiebadizi, N Mosaddeghzadeh… - Cancers, 2021 - mdpi.com
Simple Summary Whilst mutations in genes encoding RHO GTPase proteins are rare in
different type of cancers, altered expression of several RHO GTPases has been reported in …

A novel prognostic prediction model for colorectal cancer based on nine autophagy-related long noncoding RNAs

G Xu, M Yang, Q Wang, L Zhao, S Zhu, L Zhu… - Frontiers in …, 2021 - frontiersin.org
Introduction Colorectal cancer (CRC) is the most common gastrointestinal cancer and has a
low overall survival rate. Tumor–node–metastasis staging alone is insufficient to predict …