Stem cells: a historical review about biological, religious, and ethical issues

IA Charitos, A Ballini, S Cantore… - Stem Cells …, 2021 - Wiley Online Library
Stem cells can be used to replace damaged cells or regenerate organs and have
broadened our knowledge of the development and progression of certain diseases. Despite …

Neurobiology of cannabinoid receptor signaling

B Lutz - Dialogues in clinical neuroscience, 2020 - Taylor & Francis
The endocannabinoid system (ECS) is a highly versatile signaling system within the nervous
system. Despite its widespread localization, its functions within the context of distinct neural …

The interplay between the endocannabinoid system, epilepsy and cannabinoids

KA Kwan Cheung, H Peiris, G Wallace… - International journal of …, 2019 - mdpi.com
Epilepsy is a neurological disorder that affects approximately 50 million people worldwide.
There is currently no definitive epilepsy cure. However, in recent years, medicinal cannabis …

Cannabidiol-loaded injectable chitosan-based hydrogels promote spinal cord injury repair by enhancing mitochondrial biogenesis

H Zhang, T Hu, M Xiong, S Li, WX Li, J Liu… - International Journal of …, 2022 - Elsevier
The treatment of traumatic spinal cord injury (SCI) remains challenging as the neuron
regeneration is impaired by irregular cavity and apoptosis. An injectable in situ gelling …

[HTML][HTML] Cannabidiol and neurodevelopmental disorders in children

KA Kwan Cheung, MD Mitchell, HS Heussler - Frontiers in Psychiatry, 2021 - frontiersin.org
Neurodevelopmental and neuropsychiatric disorders (such as autism spectrum disorder)
have broad health implications for children, with no definitive cure for the vast majority of …

Alterations of brain endocannabinoidome signaling in germ-free mice

C Manca, M Shen, B Boubertakh, C Martin… - … et Biophysica Acta (BBA …, 2020 - Elsevier
We investigated the hypothesis that the endocannabinoidome (eCBome), an extension of
the endocannabinoid (eCB) signaling system with important functions in the CNS, may play …

Hippocampal regenerative medicine: neurogenic implications for addiction and mental disorders

L Peyton, A Oliveros, DS Choi, MH Jang - Experimental & molecular …, 2021 - nature.com
Psychiatric illness is a prevalent and highly debilitating disorder, and more than 50% of the
general population in both middle-and high-income countries experience at least one …

The therapeutic potential of the endocannabinoid system in age-related diseases

IM Tudorancea, M Ciorpac, GD Stanciu, C Caratașu… - Biomedicines, 2022 - mdpi.com
The endocannabinoid system (ECS) dynamically regulates many aspects of mammalian
physiology. ECS has gained substantial interest since growing evidence suggests that it …

[HTML][HTML] In vitro studies on therapeutic effects of cannabidiol in neural cells: neurons, glia, and neural stem cells

J Kim, H Choi, EK Kang, GY Ji, Y Kim, IS Choi - Molecules, 2021 - mdpi.com
(‒)-Cannabidiol (CBD) is one of the major phytocannabinoids extracted from the Cannabis
genus. Its non-psychoactiveness and therapeutic potential, partly along with some anecdotal …

Neurological benefits, clinical challenges, and neuropathologic promise of medical marijuana: A systematic review of cannabinoid effects in multiple sclerosis and …

V Longoria, H Parcel, B Toma, A Minhas, R Zeine - Biomedicines, 2022 - mdpi.com
Despite current therapeutic strategies for immunomodulation and relief of symptoms in
multiple sclerosis (MS), remyelination falls short due to dynamic neuropathologic …