Emerging concepts and technologies in vaccine development

M Brisse, SM Vrba, N Kirk, Y Liang, H Ly - Frontiers in immunology, 2020 - frontiersin.org
Despite the success of vaccination to greatly mitigate or eliminate threat of diseases caused
by pathogens, there are still known diseases and emerging pathogens for which the …

Impact of plant products on innate and adaptive immune system of cultured finfish and shellfish

R Harikrishnan, C Balasundaram, MS Heo - Aquaculture, 2011 - Elsevier
Aquaculture is one of the fastest growing food-producing sectors around the world. Among
various kinds of cultivated organisms many marine and freshwater finfish and shellfish …

Current status of veterinary vaccines

ENT Meeusen, J Walker, A Peters… - Clinical microbiology …, 2007 - Am Soc Microbiol
The major goals of veterinary vaccines are to improve the health and welfare of companion
animals, increase production of livestock in a cost-effective manner, and prevent animal-to …

[HTML][HTML] DNA vaccines: roles against diseases

KH Khan - Germs, 2013 - ncbi.nlm.nih.gov
Vaccination is the most successful application of immunological principles to human health.
Vaccine efficacy needs to be reviewed from time to time and its safety is an overriding …

The silencing of cysteine proteases in Fasciola hepatica newly excysted juveniles using RNA interference reduces gut penetration

L McGonigle, A Mousley, NJ Marks, GP Brennan… - International journal for …, 2008 - Elsevier
Probing protein function in parasitic flatworms is hampered by the difficulties associated with
the development of transgenic approaches. Although RNA interference (RNAi) in …

Fasciola hepatica Extracellular Vesicles isolated from excretory-secretory products using a gravity flow method modulate dendritic cell phenotype and activity

A Murphy, K Cwiklinski, R Lalor… - PLoS neglected …, 2020 - journals.plos.org
Parasite-released extracellular vesicles (EVs) deliver signals to the host immune system that
are critical to maintaining the long-term relationship between parasite and host. In the …

Biomedical applications of sheep models: from asthma to vaccines

JPY Scheerlinck, KJ Snibson, VM Bowles… - Trends in …, 2008 - cell.com
Although rodent models are very popular for scientific studies, it is becoming more evident
that large animal models can provide unique opportunities for biomedical research. Sheep …

Vaccine development: Current trends and technologies

R Poria, D Kala, R Nagraik, Y Dhir, S Dhir, B Singh… - Life Sciences, 2023 - Elsevier
Despite the effectiveness of vaccination in reducing or eradicating diseases caused by
pathogens, there remain certain diseases and emerging infections for which developing …

Electroporation-enhanced nonviral gene transfer for the prevention or treatment of immunological, endocrine and neoplastic diseases

GJ Prud'homme, Y Glinka, AS Khan… - Current Gene …, 2006 - ingentaconnect.com
Nonviral gene transfer is markedly enhanced by the application of in vivo electroporation
(also denoted electrogene transfer or electrokinetic enhancement). This approach is safe …

A distinctive repertoire of cathepsins is expressed by juvenile invasive Fasciola hepatica

M Cancela, D Acosta, G Rinaldi, E Silva, R Durán… - Biochimie, 2008 - Elsevier
Secreted cysteine proteases are relevant actors in parasite biology, taking part in critical
host colonization roles such as traversing tissue barriers, immune evasion and nutrient …