Recent advances of oral film as platform for drug delivery

M He, L Zhu, N Yang, H Li, Q Yang - International Journal of Pharmaceutics, 2021 - Elsevier
Orally drug delivery film has received extensive interest duo to a distinct set of its
advantageous properties compared to the traditional orally administered dosages, including …

Clinical manifestation, evaluation, and rehabilitative strategy of dysphagia associated with COVID-19

Y Aoyagi, Y Inamoto, S Shibata, H Kagaya… - American Journal of …, 2021 - journals.lww.com
Dysphagia is the difficulty in swallowing because of the presence of certain diseases; it
particularly compromises the oral and/or pharyngeal stages. In severe acute respiratory …

Using high resolution manometry impedance to diagnose upper esophageal sphincter and pharyngeal motor disorders

T Omari, C Cock, P Wu, MM Szczesniak… - …, 2023 - Wiley Online Library
Background Oro‐pharyngeal pathophysiology, including upper esophageal sphincter (UES)
and pharyngeal disorders, can be assessed by pharyngeal high‐resolution manometry …

Modulation of pharyngeal swallowing by bolus volume and viscosity

L Ferris, S Doeltgen, C Cock… - American Journal …, 2021 - journals.physiology.org
Oropharyngeal swallowing involves complex neuromodulation to accommodate changing
bolus characteristics. The pressure events during deglutitive pharyngeal reconfiguration and …

Development and evaluation of amorphous oral thin films using solvent-free processes: comparison between 3D printing and hot-melt extrusion technologies

J Zhang, A Lu, R Thakkar, Y Zhang, M Maniruzzaman - Pharmaceutics, 2021 - mdpi.com
Conventional oral dosage forms may not always be optimal especially for those patients
suffering from dysphasia or difficulty swallowing. Development of suitable oral thin films …

Effect of tongue-hold swallow on pharyngeal contractile properties in healthy individuals

Y Aoyagi, M Ohashi, S Ando, Y Inamoto, K Aihara… - Dysphagia, 2021 - Springer
Tongue-hold swallow (THS) is a swallow exercise in which an individual swallows saliva
while holding the anterior portion of the tongue between the front teeth. The effect of THS on …

An overview of in vitro dissolution testing for film dosage forms

W Zhang, C Xiao, Y Xiao, B Tian, D Gao, W Fan… - Journal of Drug Delivery …, 2022 - Elsevier
Films are a rapidly developing new dosage form, with dozens of products marketed
worldwide in the past two decades. Dissolution is a critical quality attribute of film dosage …

Impact of early tracheostomy on outcomes after cardiac surgery: a national analysis

S Sareh, W Toppen, R Ugarte, Y Sanaiha… - The Annals of Thoracic …, 2021 - Elsevier
Background Despite evidence supporting its early use in respiratory failure, tracheostomy is
often delayed in cardiac surgical patients given concerns for sternal infection. This study …

Impact of tracheostomy timing on outcomes after cardiovascular surgery

M Okada, H Watanuki, T Masato, K Sugiyama… - Journal of cardiothoracic …, 2022 - Elsevier
Objectives This study aimed to investigate whether tracheostomy timing in patients
undergoing cardiac surgery had an impact on outcomes. Design Retrospective …

[HTML][HTML] Biowaiver based on biopharmaceutics classification system: Considerations and requirements

PR Dhake, ST Kumbhar, VL Gaikwad - Pharmaceutical Science Advances, 2023 - Elsevier
Biowaiver allows for the waiver of bioequivalence studies for regulatory approval of certain
drug products with saving of time, and money. Before approval of the application for …