Plants represent the main source of molecules for the development of new drugs, which
intensifies the interest of transnational industries in searching for substances obtained from …

Autoimmune diseases (ADs) are characterized by the production of autoreactive
lymphocytes, immune responses to self-antigens, and inflammation in related tissues and …

Vitamin B6 is a cofactor for approximately 150 reactions that regulate the metabolism of
glucose, lipids, amino acids, DNA, and neurotransmitters. In addition, it plays the role of …

Type 1 diabetes (T1D) is a multifactorial autoimmune disease driven by T-cells against the
insulin-producing islet β-cells, resulting in a marked loss of β-cell mass and function …

Diabetes mellitus (type 1 and type 2) and its various complications continue to place a huge
burden on global medical resources, despite the availability of numerous drugs that …

Extracellular vesicles (EVs) are implicated in the crosstalk between adipocytes and other
metabolic organs, and an altered biological cargo has been observed in EVs from human …

Impaired bone healing occurs in 5–10% of cases following injury, leading to a significant
economic and clinical impact. While an inflammatory response upon injury is necessary to …

Simple Summary Inflammation is like the proverbial double-edged sword. Controlled short-
term inflammation could be a protective response while uncontrolled inflammation sustains …

Type 1-diabetes (T1D) is an autoimmune disease characterized by immune-mediated
destruction of pancreatic beta (β)-cells. Genetic and environmental interactions play an …

Understanding the root causes of autoimmune diseases is hampered by the inability to
access relevant human tissues and identify the time of disease onset. To examine the …