The microbiome may impact cancer development, progression and treatment
responsiveness, but its fungal components remain insufficiently studied in this context. In this …

Microorganisms are effective platforms for the production of a variety of chemicals including
biofuels, commodity chemicals, polymers and other natural products. However, deep cellular …

Microbial cell factories provide a green and sustainable opportunity to produce value‐added
products from renewable feedstock. However, the leakage of toxic or volatile intermediates …

In the yeast Saccharomyces cerevisiae, terminator sequences not only terminate
transcription but also affect expression levels of the protein-encoded upstream of the …

The optimization of cellular functions often requires the balancing of gene expression, but
the physical construction and screening of alternative designs are costly and time …

Background Tailoring gene expression to balance metabolic fluxes is critical for the
overproduction of metabolites in yeast hosts, and its implementation requires coordinated …

Sandalwood oil has been widely used in perfumery industries and aromatherapy. Santalols
are its major components. Herein, we attempted to construct santalol-producing yeasts. To …

Natural products continue to be the inspirations for us to discover and acquire new drugs.
The seemingly unstoppable viruses have kept records high to threaten human health and …

Organisms have developed effective mechanisms to sense the external environment.
Human-designed biosensors exploit this natural optimization, where different biological …

Bioethanol production from starchy biomass via consolidated bioprocessing (CBP) will
benefit from amylolytic Saccharomyces cerevisiae strains that produce high levels of …