Pharmacokinetics and pharmacodynamics of direct oral anticoagulants

B Hindley, GYH Lip, AP McCloskey… - Expert Opinion on Drug …, 2023 - Taylor & Francis
ABSTRACT Introduction Direct oral anticoagulants (DOACs) have overtaken vitamin K
antagonists to become the most widely used method of anticoagulation for most indications …

Comparative efficacy and safety of measures for the treatment of adults with isolated calf muscular vein thrombosis: a systematic review and network meta-analysis

Z Huang, M Chen, H Sun, D Li, Z Cai, Z Lin, F Liu… - Annals of Vascular …, 2023 - Elsevier
Introduction Isolated calf muscular vein thrombosis (ICMVT) can result in pulmonary
embolism (PE), but the treatment of ICMVT remains controversial. Therefore, the purpose of …

Real life results of direct-acting oral anticoagulants recommended-dose in obese vs normal-weight patients with venous thromboembolism

JA Rueda-Camino, R Barba, S Otálora… - Thrombosis …, 2024 - Elsevier
Background There is scarce evidence on the effectiveness and safety of recommended-
dose direct acting oral anticoagulants (DOACs) in obese patients with venous …

Primary Care Clinicians' Prescribing Patterns of Reduced-Dose Direct Oral Anticoagulants for Extended-Phase Venous Thromboembolism Treatment

D Groat, KA Martin, RP Rosovsky… - Journal of Clinical …, 2023 - mdpi.com
The direct anticoagulants (DOACs), apixaban and rivaroxaban, are used for extended-
phase treatment of venous thromboembolism (VTE) and have labeling for dose reduction for …

Übergewicht: Einsatz von DOAK bei Venen-thrombose

S Burgess - thieme-connect.com
Bei tiefen Beinvenenthrombosen ist der Einsatz der 4 direkten oralen Antikoagulantien
Apixaban, Dabigatran, Rivaroxaban und Edoxaban zum Standard geworden. Bei …