Inflammation: A new look at an old problem

E Gusev, Y Zhuravleva - International Journal of Molecular Sciences, 2022 - mdpi.com
Pro-inflammatory stress is inherent in any cells that are subject to damage or threat of
damage. It is defined by a number of universal components, including oxidative stress …

Organophosphorus pesticides as modulating substances of inflammation through the cholinergic pathway

MR Camacho-Pérez, CE Covantes-Rosales… - International Journal of …, 2022 - mdpi.com
Organophosphorus pesticides (OPs) are widespread insecticides used for pest control in
agricultural activities and the control of the vectors of human and animal diseases. However …

Pesticide pollution: detrimental outcomes and possible mechanisms of fish exposure to common organophosphates and triazines

I Khatib, P Rychter, H Falfushynska - Journal of Xenobiotics, 2022 - mdpi.com
Pesticides are well known for their high levels of persistence and ubiquity in the
environment, and because of their capacity to bioaccumulate and disrupt the food chain …

Recent advances in cholinergic mechanisms as reactions to toxicity, stress, and neuroimmune insults

Z Kovarik, G Moshitzky, N Maček Hrvat… - Journal of …, 2024 - Wiley Online Library
This review presents recent studies of the chemical and molecular regulators of
acetylcholine (ACh) signaling and the complexity of the small molecule and RNA regulators …

Cognitive impairment and neurodegenerative diseases development associated with organophosphate pesticides exposure: a review study

M Sarailoo, S Afshari, V Asghariazar… - Neurotoxicity …, 2022 - Springer
A significant body of literature emphasizes the role of insecticide, particularly
organophosphates (OPs), as the major environmental factor in the etiology of …

Impact of environmental toxicants on p38-and ERK-MAPK signaling pathways in the central nervous system

OM Ijomone, JD Iroegbu, M Aschner, J Bornhorst - Neurotoxicology, 2021 - Elsevier
There are several candidate signalling pathways that mediate the response of the central
nervous system (CNS) cells to environmental toxins. However, much is still to be learned on …

[HTML][HTML] Effects of chlorantraniliprole-based pesticide on transcriptional response and gut microbiota of the crucian carp, Carassius carassius

H Yin, Y Huang, G Yan, Q Huang, Y Wang, H Liu… - Ecotoxicology and …, 2023 - Elsevier
Chlorantraniliprole (CAP) is a presentative diamide pesticide utilized in agricultural area and
as well as rice-fish co-culture system for pest control. However, the understanding of toxic …

Transcriptome reveals key microRNAs involved in fat deposition between different tail sheep breeds

X Fei, M Jin, Y Wang, T Li, Z Lu, Z Yuan, H Wang, J Lu… - PloS one, 2022 - journals.plos.org
MicroRNA (miRNA) is a kind of noncoding RNA whose function involved in various
biological processes in neuronal maturation and adipocyte cells, such as differentiation …

[HTML][HTML] Cadmium induces testosterone synthesis disorder by testicular cell damage via TLR4/MAPK/NF-κB signaling pathway leading to reduced sexual behavior in …

Y Li, Y Zhang, R Feng, P Zheng, H Huang… - Ecotoxicology and …, 2022 - Elsevier
Cadmium (Cd) is a highly toxic metal pollutant that can endanger the life and health of
animals. Toll-like receptor 4 (TLR4) can result in testicular cell damage by positively …

Molecular mechanisms of acute organophosphate nephrotoxicity

VE Sobolev, MO Sokolova, RO Jenkins… - International Journal of …, 2022 - mdpi.com
Organophosphates (OPs) are toxic chemicals produced by an esterification process and
some other routes. They are the main components of herbicides, pesticides, and insecticides …