Therapeutic strategies to protect the ischemic myocardium have been studied extensively.
Reperfusion is the definitive treatment for acute coronary syndromes, especially acute …

Diabetes has emerged as a major threat to worldwide health. The increasing incidence of
diabetes in young individuals is particularly worrisome given that the disease is likely to …

Metformin is now established as a first-line antidiabetic therapy for the management of type
2 diabetes. Its early use in treatment algorithms is supported by lack of weight gain, low risk …

Apoptosis plays a key role in the pathogenesis in a variety of cardiovascular diseases due to
loss of terminally differentiated cardiac myocytes. Cardiac myocytes undergoing apoptosis …

A hyperglycemic state, also in non-diabetic subjects, may be associated with acute coronary
syndrome (ACS). Aim of this review is to describe the pathophysiologic association between …

Diabetic cardiomyopathy is a distinct primary disease process, independent of coronary
artery disease, which leads to heart failure in diabetic patients. Epidemiological and clinical …

Human mesenchymal stem cells (MSCs) have the potential for improving cardiac function
following myocardial infarction (MI). This study was performed to explore the …

Despite the significant decline in mortality, cardiovascular diseases are still the leading
cause of death worldwide. Among them, myocardial infarction (MI) seems to be the most …

Both incidence and mortality of acute coronary syndrome (ACS) among diabetic patients are
much higher than those among nondiabetics. Actually, there are many studies that …

Background Diabetes mellitus (DM) and hypertension (HTN) are accused of being
responsible for the development of the cardiac fibrosis due to severe cardiomyopathy …