Background The effects of streptozotocin (STZ)-induced diabetes on heart metabolism and
function after myocardial infarction (MI) remodelling were investigated in rats. Methods …

Background Myocardial infarction increases the risk of heart failure (HF) and atrial
fibrillation. Renal denervation (RDN) might suppress the development of atrial remodeling …

Hyperglycemia (HG) significantly increases mortality after myocardial infarction (MI) in
patients with and without established diabetes. The specific underlying mechanism remains …

Type 2 diabetes mellitus (T2DM) is a major risk factor for developing cardiovascular disease
and represents a serious public health problem, with high rates of mortality and morbidity …

Heme oxygenase-1 (HO-1) is a cytoprotective enzyme, which regulates cell proliferation and
has potential antifibrogenic properties. In the present study, we investigated the effects of pre …

Diabetes mellitus (DM) is an increasing epidemic that places a significant burden on health
services worldwide. The incidence of heart failure (HF) is significantly higher in diabetic …

The medical treatment of heart failure (HF) is associated with 50% survival at 5 years, thus
being one of the major causes of mortality in Western countries. An understanding of the …

Background Previous research has demonstrated that hyperglycemia may protect the heart
against ischemic injury. The aim of the present study was to investigate the association …

Increased myocyte apoptosis in diabetic hearts has been previously reported. Therefore, the
purpose of this study was to evaluate the effects of insulin on cardiac apoptotic, hypertrophic …

Cardiovascular diseases (CVDs) have a complex pathogenesis and pose a major threat to
human health. Cardiomyocytes have a low regenerative capacity, and their death is a key …