Consensus statement on indications for anti-angiogenic therapy in the management of corneal diseases associated with neovascularisation: outcome of an expert …

C Cursiefen, J Colin, R Dana, M Diaz-Llopis… - British journal of …, 2012 - bjo.bmj.com
The cornea is the clear window at the front of the eye and is the eye's main refractive
medium. Its transparency is essential for vision. Corneal neovascularisation is a common …

Hydrogen and N-acetyl-L-cysteine rescue oxidative stress-induced angiogenesis in a mouse cornealalkali-burn model

M Kubota, S Shimmura, S Kubota… - … & visual science, 2011 - iovs.arvojournals.org
Purpose.: To investigate the role of reactive oxygen species (ROS) as the prime initiators of
the angiogenic response after alkali injury of the cornea and observe the effects of …

Netrin-1 simultaneously suppresses corneal inflammation and neovascularization

Y Han, Y Shao, Z Lin, YL Qu, H Wang… - … & visual science, 2012 - iovs.arvojournals.org
Purpose.: To investigate the effect of netrin-1 on alkali burn-induced corneal inflammation
and neovascularization. Methods.: The expression of netrin-1 and its receptors UNC5A …

B cells, dendritic cells, and macrophages are required to induce an autoreactive CD4 helper T cell response in experimental epidermolysis bullosa acquisita

H Iwata, K Bieber, B Tiburzy, N Chrobok… - The Journal of …, 2013 - journals.aai.org
In autoimmune bullous dermatoses (AIBD), autoantibodies induce blisters on skin or
mucous membranes, or both. Mechanisms of continued autoantibody production and …

Depletion of CD4 T cells provides therapeutic benefits in aged mice after ischemic stroke

NM Harris, M Roy-O'Reilly, RM Ritzel, A Holmes… - Experimental …, 2020 - Elsevier
T-lymphocytes have a multifaceted role in ischemic stroke, but the majority of studies have
been conducted in young mice, which may limit the translational value of these findings …

Corneal angiogenesis: etiologies, complications and management

S Feizi - Physiologic and Pathologic Angiogenesis-Signaling …, 2017 - books.google.com
A large subset of corneal pathologies involves the formation of new blood vessels, leading
to compromised visual acuity. Additionally, neovascularization of the cornea worsens the …

β-defensin 2 as an Adjuvant Promotes Anti-Melanoma Immune Responses and Inhibits the Growth of Implanted Murine Melanoma In Vivo

H Mei, X Jin, J Zhu, A Zeng, Q Wu, X Lu, X Li, J Shen - PloS one, 2012 - journals.plos.org
β-defensin 2 is a small antimicrobial peptide of the innate immune system and has been
thought to regulate anti-tumor immunity. However, little is known on whether β-defensin 2 …

[HTML][HTML] PEP-1-FK506BP inhibits alkali burn-induced corneal inflammation on the rat model of corneal alkali injury

DW Kim, SH Lee, MJ Shin, K Kim, SK Ku, JK Youn… - BMB …, 2015 - ncbi.nlm.nih.gov
Abstract FK506 binding protein 12 (FK506BP) is a small peptide with a single FK506BP
domain that is involved in suppression of immune response and reactive oxygen species …

[HTML][HTML] Fasudil hydrochloride, a potent ROCK inhibitor, inhibits corneal neovascularization after alkali burns in mice

P Zeng, R Pi, P Li, R Chen, L Lin, H He, S Zhou - Molecular vision, 2015 - ncbi.nlm.nih.gov
METHODS Animals: Female BALB/c mice aged 4 to 6 weeks and weighting between 16 and
20 g were purchased from the Guangdong Provincial Center for Animal Research in …

[HTML][HTML] Rapamycin prevents endothelial cell migration by inhibiting the endothelial-to-mesenchymal transition and matrix metalloproteinase-2 and-9: an in vitro study

H Gao, J Zhang, T Liu, W Shi - Molecular Vision, 2011 - ncbi.nlm.nih.gov
Purpose To evaluate the influence of rapamycin on endothelial-mesenchymal transition and
matrix metalloproteinase (MMP) secretion by human umbilical vein endothelial cell line EA …