Crohn's disease and ulcerative colitis, phenotypically comprising a spectrum of inflammatory
bowel diseases (IBDs), spread globally during the westernization of lifestyle and dietary …

Bioactive peptides are biomolecules derived from proteins. They contain anywhere from 2 to
20 amino acids and have different bioactivities. For example, they have antihypertensive …

The human gut microbiota continues to demonstrate its importance in human health and
disease, largely owing to the countless number of studies investigating the fecal microbiota …

The mechanisms by which the early-life microbiota protects against environmental factors
that promote childhood obesity remain largely unknown. Using a mouse model in which …

Background Upper small intestinal dietary lipids activate a gut-brain axis regulating energy
homeostasis. The prebiotic, oligofructose (OFS) improves body weight and adiposity during …

Systemic metabolism has to be constantly adjusted to the variance of food intake and even
be prepared for anticipated changes in nutrient availability. Therefore, the brain integrates …

Obesity currently represents a major societal and health challenge worldwide. Its prevalence
has reached epidemic proportions and trends continue to rise, reflecting the need for more …

The gut microbiota acts as a symbiotic microecosystem that plays an indispensable role in
the regulation of a number of metabolic processes in the host by secreting secondary …

Type 2 diabetes rates continue to rise unabated, underscoring the need to better understand
the etiology and potential therapeutic options available for this disease. The gut microbiome …

Equine insulin dysregulation (ID) comprises amplified insulin responses to oral
carbohydrates or insulin resistance, or both, which leads to sustained or periodic …