Abstract P2Y receptors are G-protein-coupled receptors (GPCRs) for extracellular
nucleotides. There are eight mammalian P2Y receptor subtypes (P2Y 1, P2Y 2, P2Y 4, P2Y …

There have been many advances in our knowledge about different aspects of P2Y receptor
signaling since the last review published by our International Union of Pharmacology …

Membrane-bound P2-receptors mediate the actions of extracellular nucleotides in cell-to-
cell signalling. P2X-receptors are ligand-gated ion channels, whereas P2Y-receptors belong …

Membrane-bound P2-receptors mediate the actions of extracellular nucleotides in cell-to-
cell signalling. P2X-receptors are ligand-gated ion channels, whereas P2Y-receptors belong …

The human P2Y11 receptor is coupled to both the phosphoinositide and the cyclic AMP
pathways. A pharmacological characterization of the recombinant human P2Y11 receptor …

The P2Y receptors are a widely expressed group of eight nucleotide-activated G protein-
coupled receptors (GPCRs). The P2Y 1 (ADP), P2Y 2 (ATP/UTP), P2Y 4 (UTP), P2Y 6 …

ATP is known to act as an extracellular messenger mediating the propagation of Ca2+
waves in astrocyte networks. ATP mediates Ca2+ waves by activating P2Y purinoceptors …

Pyrimidine nucleotides, including UTP, UDP and UDP-glucose, are important signaling
molecules which activate G protein-coupled membrane receptors (GPCRs) of the P2Y …

Nucleotides are ubiquitous intercellular messengers whose actions are mediated by specific
receptors. Since the first clonings in 1993, it is known that nucleotide receptors belong to two …

Abstract P2Y receptors (P2YRs) are a family of G protein-coupled receptors activated by
extracellular nucleotides. Physiological P2YR agonists include purine and pyrimidine …