[HTML][HTML] The role of antioxidants in the interplay between oxidative stress and senescence

A Varesi, S Chirumbolo, LIM Campagnoli, E Pierella… - Antioxidants, 2022 - mdpi.com
Cellular senescence is an irreversible state of cell cycle arrest occurring in response to
stressful stimuli, such as telomere attrition, DNA damage, reactive oxygen species, and …

[HTML][HTML] A pharmacological update of ellagic acid

JL Ríos, RM Giner, M Marín, MC Recio - Planta medica, 2018 - thieme-connect.com
Ellagic acid is a common metabolite present in many medicinal plants and vegetables. It is
present either in free form or as part of more complex molecules (ellagitannins), which can …

[HTML][HTML] Neuroprotective potential of ellagic acid: a critical review

A Gupta, AK Singh, R Kumar, S Jamieson… - Advances in …, 2021 - Elsevier
Ellagic acid (EA) is a dietary polyphenol present in various fruits, vegetables, herbs, and
nuts. It exists either independently or as part of complex structures, such as ellagitannins …

[HTML][HTML] Ellagic acid ameliorates oxidative stress and insulin resistance in high glucose-treated HepG2 cells via miR-223/keap1-Nrf2 pathway

X Ding, T Jian, Y Wu, Y Zuo, J Li, H Lv, L Ma… - Biomedicine & …, 2019 - Elsevier
As a promising new target, miR-233 may regulate oxidative stress by targeting keap1-Nrf2
system to affect the pathological process of liver injury in T2DM. Ellagic acid (EA) is versatile …

Antidiabetic effects of simple phenolic acids: A comprehensive review

R Vinayagam, M Jayachandran, B Xu - Phytotherapy research, 2016 - Wiley Online Library
Diabetes mellitus (DM) has become a major public health threat across the globe. Current
antidiabetic therapies are based on synthetic drugs that very often have side effects. It has …

Updates on aldose reductase inhibitors for management of diabetic complications and non-diabetic diseases

A Singh Grewal, S Bhardwaj, D Pandita… - Mini reviews in …, 2016 - ingentaconnect.com
Diabetes mellitus occurrence has been associated to the modification of the physiological
levels of glucose and is often accompanied by several long-term complications, namely …

[HTML][HTML] Ellagic acid alleviates oxidative stress by mediating Nrf2 signaling pathways and protects against paraquat-induced intestinal injury in piglets

Y Xiao, R Huang, N Wang, Y Deng, B Tan, Y Yin, M Qi… - Antioxidants, 2022 - mdpi.com
The gastrointestinal tract is a key source of superoxide so as to be one of the most
vulnerable to oxidative stress damage. Ellagic acid (EA), a polyphenol displays widely …

[HTML][HTML] Ellagic acid as a tool to limit the diabetes burden: Updated evidence

AJ Amor, C Gómez-Guerrero, E Ortega, A Sala-Vila… - Antioxidants, 2020 - mdpi.com
Oxidative stress contributes not only to the pathogenesis of type 2 diabetes (T2D) but also to
diabetic vascular complications. It follows that antioxidants might contribute to limiting the …

Neurological effects of honey: current and future prospects

M Mijanur Rahman, SH Gan… - … and Alternative Medicine, 2014 - Wiley Online Library
Honey is the only insect‐derived natural product with therapeutic, traditional, spiritual,
nutritional, cosmetic, and industrial value. In addition to having excellent nutritional value …

[HTML][HTML] Anthocyanins as antidiabetic agents—in vitro and in silico approaches of preventive and therapeutic effects

H Oliveira, A Fernandes, N F. Brás, N Mateus… - Molecules, 2020 - mdpi.com
Many efforts have been made in the past two decades into the search for novel natural and
less-toxic anti-diabetic agents. Some clinical trials have assigned this ability to …