Klebsiella pneumoniae infection biology: living to counteract host defences

JA Bengoechea, J Sa Pessoa - FEMS microbiology reviews, 2019 - academic.oup.com
Klebsiella species cause a wide range of diseases including pneumonia, urinary tract
infections (UTIs), bloodstream infections and sepsis. These infections are particularly a …

The past, present and future of Dictyostelium as a model system

S Bozzaro - The International Journal of Developmental Biology, 2019 - iris.unito.it
The social amoeba Dictyostelium discoideum has been a preferred model organism during
the last 50 years, particularly for the study of cell motility and chemotaxis, phagocytosis and …

Exploiting Zebrafish Xenografts for Testing the in vivo Antitumorigenic Activity of Microcin E492 Against Human Colorectal Cancer Cells

MA Varas, C Muñoz-Montecinos, V Kallens… - Frontiers in …, 2020 - frontiersin.org
One of the approaches to address cancer treatment is to develop new drugs not only to
obtain compounds with less side effects, but also to have a broader set of alternatives to …

Baicalein resensitizes multidrug-resistant gram-negative pathogens to doxycycline

Y Wang, J Su, Z Zhou, J Yang, W Liu… - Microbiology …, 2023 - Am Soc Microbiol
As multidrug-resistant pathogens emerge and spread rapidly, novel antibiotics urgently
need to be discovered. With a dwindling antibiotic pipeline, antibiotic adjuvants might be …

Ultrashort Cationic Lipopeptides–Effect of N-Terminal Amino Acid and Fatty Acid Type on Antimicrobial Activity and Hemolysis

D Neubauer, M Jaśkiewicz, M Bauer, K Gołacki… - Molecules, 2020 - mdpi.com
Ultrashort cationic lipopeptides (USCLs) are promising antimicrobial agents that
hypothetically may be alternatively used to combat pathogens such as bacteria and fungi. In …

Analysis of the Oxidative Stress Regulon Identifies soxS as a Genetic Target for Resistance Reversal in Multidrug-Resistant Klebsiella pneumoniae

J Anes, K Dever, A Eshwar, S Nguyen, Y Cao… - MBio, 2021 - Am Soc Microbiol
In bacteria, the defense system deployed to counter oxidative stress is orchestrated by three
transcriptional factors, SoxS, SoxR, and OxyR. Although the regulon that these factors …

[HTML][HTML] Association of sequence types, antimicrobial resistance and virulence genes in Indian isolates of Klebsiella pneumoniae: A comparative genomics study

AK Sundaresan, K Vincent, GBM Mohan… - Journal of Global …, 2022 - Elsevier
Objectives Klebsiella pneumoniae genomic surveillance in India was performed to
understand the spread of antimicrobial resistant genes across the country over 10 years and …

Klebsiella virus UPM2146 lyses multiple drug-resistant Klebsiella pneumoniae in vitro and in vivo

O Assafiri, AAL Song, GH Tan, I Hanish, AM Hashim… - Plos one, 2021 - journals.plos.org
Klebsiella pneumoniae are opportunistic bacteria found in the gut. In recent years they have
been associated with nosocomial infections. The increased incidence of multiple drug …

Zebrafish and Galleria mellonella: Models to Identify the Subsequent Infection and Evaluate the Immunological Differences in Different Klebsiella pneumoniae …

X Zhang, Y Zhao, Q Wu, J Lin, R Fang, W Bi… - Frontiers in …, 2019 - frontiersin.org
The intestine is the main reservoir of bacterial pathogens in most organisms. Klebsiella
pneumoniae is an important opportunistic pathogen associated with nosocomial bacterial …

[HTML][HTML] An in vitro study of molecular effects of a combination treatment with antibiotics and nanofluid containing carbon nano-tubes on klebsiella pneumoniae

M Mehdizadeh, M Sheikhpour… - Iranian Journal of …, 2021 - ncbi.nlm.nih.gov
Background: We aimed to prepare a nanofluid, containing f-MWCNTs, and investigate the
antibacterial efficacy of f-MWCNTs+ ciprofloxacin (cip) on Klebsiella pneumoniae by …