CD8+ T cells are the key executioners of the adaptive immune arm, which mediates
antitumor and antiviral immunity. Naïve CD8+ T cells develop in the thymus and are quickly …

Cytotoxic CD8+ T cells recognize and eliminate infected or cancerous cells. A subset of
CD8+ memory T cells called tissue‐resident memory T cells (TRM) resides in peripheral …

Intraepithelial lymphocytes (IELs), including αβ and γδ T cells (T-IELs), constantly survey
and play a critical role in maintaining the gastrointestinal epithelium. We show that cytotoxic …

The oral mucosa is a frontline for microbial exposure and juxtaposes several unique tissues
and mechanical structures. Based on parabiotic surgery of mice receiving systemic viral …

Cryptosporidium causes debilitating diarrheal disease in patients with primary and acquired
defects in T cell function. However, it has been a challenge to understand how this infection …

Tissue‐resident memory T cells (TRM) represent a dedicated layer of localized immune
memory in virtually every organ throughout the human body. By virtue of their long‐term …

Primary Sjogren's syndrome (pSS) is a complex chronic autoimmune disease in which local
tissue damage in exocrine glands is combined with broader systemic involvement across …

Tissue-resident memory T (Trm) cells are a subset of T cells maintained throughout life
within nonlymphoid tissues without significant contribution from circulating memory T cells …

IL-1R integrates signals from IL-1α and IL-1β, and it is widely expressed across tissues and
immune cell types. While the expression pattern and function of IL-1R within the innate …

Abstract Introduction Resident memory T (T RM) cells are embedded in peripheral tissue
and capable of acting as sentinels that can respond quickly to repeat pathogen exposure as …