Internal state dependent odor processing and perception—The role of neuromodulation in the fly olfactory system

S Sayin, AC Boehm, JM Kobler… - Frontiers in cellular …, 2018 - frontiersin.org
Animals rely heavily on their sense of olfaction to perform various vital interactions with an
ever-in-flux environment. The turbulent and combinatorial nature of air-borne odorant cues …

Synaptic Orb2A bridges memory acquisition and late memory consolidation in Drosophila

S Krüttner, L Traunmüller, U Dag, K Jandrasits… - Cell reports, 2015 - cell.com
To adapt to an ever-changing environment, animals consolidate some, but not all, learning
experiences to long-term memory. In mammals, long-term memory consolidation often …

Initiated by CREB: resolving gene regulatory programs in learning and memory: switch in cofactors and transcription regulators between memory consolidation and …

JC Kaldun, SG Sprecher - BioEssays, 2019 - Wiley Online Library
Consolidation of long‐term memory is a highly and precisely regulated multistep process.
The transcription regulator cAMP response element‐binding protein (CREB) plays a key role …

A pair of dopamine neurons mediate chronic stress signals to induce learning deficit in Drosophila melanogaster

J Jia, L He, J Yang, Y Shuai, J Yang… - Proceedings of the …, 2021 - National Acad Sciences
Chronic stress could induce severe cognitive impairments. Despite extensive investigations
in mammalian models, the underlying mechanisms remain obscure. Here, we show that …

Roles of feedback and feed-forward networks of dopamine subsystems: insights from Drosophila studies

AM Davidson, T Hige - Learning & Memory, 2024 - learnmem.cshlp.org
Across animal species, dopamine-operated memory systems comprise anatomically
segregated, functionally diverse subsystems. Although individual subsystems could operate …

[HTML][HTML] Changing memories on the fly: the neural circuits of memory re-evaluation in Drosophila melanogaster

J Felsenberg - Current opinion in neurobiology, 2021 - Elsevier
Highlights•Initial memory traces support subsequent aversive learning.•Acquisition of
learned avoidance gates safety learning.•Dopamine-driven extinction learning leads to the …

[HTML][HTML] Appetitive olfactory learning and memory in the honeybee depend on sugar reward identity

NK Simcock, H Gray, S Bouchebti, GA Wright - Journal of Insect Physiology, 2018 - Elsevier
One of the most important tasks of the brain is to learn and remember information associated
with food. Studies in mice and Drosophila have shown that sugar rewards must be …

An integrative sensor of body states: how the mushroom body modulates behavior depending on physiological context

R Suárez-Grimalt, ICG Kadow… - Learning & …, 2024 - learnmem.cshlp.org
The brain constantly compares past and present experiences to predict the future, thereby
enabling instantaneous and future behavioral adjustments. Integration of external …

Odor-taste learning in Drosophila larvae

A Widmann, K Eichler, M Selcho, AS Thum… - Journal of insect …, 2018 - Elsevier
The Drosophila larva is an attractive model system to study fundamental questions in the
field of neuroscience. Like the adult fly, the larva offers a seemingly unlimited genetic …

Voluntary intake of psychoactive substances is regulated by the dopamine receptor Dop1R1 in Drosophila

M Kanno, S Hiramatsu, S Kondo, H Tanimoto… - Scientific reports, 2021 - nature.com
Dysregulated motivation to consume psychoactive substances leads to addictive behaviors
that often result in serious health consequences. Understanding the neuronal mechanisms …