Promising applications of tumor spheroids and organoids for personalized medicine
Simple Summary Presently, the investigation of the tumor is carried out using different
models. One of the promising areas is the creation of 3D tumor models, such as spheroids …
models. One of the promising areas is the creation of 3D tumor models, such as spheroids …
Generation of multicellular breast cancer tumor spheroids: comparison of different protocols
K Froehlich, JD Haeger, J Heger, J Pastuschek… - Journal of mammary …, 2016 - Springer
Multicellular tumor spheroids are widely used models in tumor research. Because of their
three dimensional organization they can simulate avascular tumor areas comprising …
three dimensional organization they can simulate avascular tumor areas comprising …
Characterization of triple-negative breast cancer MDA-MB-231 cell spheroid model
Z Huang, P Yu, J Tang - OncoTargets and therapy, 2020 - Taylor & Francis
Background: The tumor three-dimensional (3D) spheroid model in vitro is effective on
detecting malignant cells and tumorigenesis, and assessing drug resistance. Compared with …
detecting malignant cells and tumorigenesis, and assessing drug resistance. Compared with …
3D tumor models: history, advances and future perspectives
P Benien, A Swami - Future oncology, 2014 - Taylor & Francis
Evaluation of cancer therapeutics by utilizing 3D tumor models, before clinical studies, could
be more advantageous than conventional 2D tumor models (monolayer cultures). The 3D …
be more advantageous than conventional 2D tumor models (monolayer cultures). The 3D …
Optimization of liquid overlay technique to formulate heterogenic 3D co‐cultures models
EC Costa, VM Gaspar, P Coutinho… - Biotechnology and …, 2014 - Wiley Online Library
ABSTRACT Three‐dimensional (3D) cell culture models of solid tumors are currently having
a tremendous impact in the in vitro screening of candidate anti‐tumoral therapies. These 3D …
a tremendous impact in the in vitro screening of candidate anti‐tumoral therapies. These 3D …
Direct measurements of oxygen gradients in spheroid culture system using electron parametric resonance oximetry
Advanced in vitro culture from tissues of different origin includes three-dimensional (3D)
organoid micro structures that may mimic conditions in vivo. One example of simple 3D …
organoid micro structures that may mimic conditions in vivo. One example of simple 3D …
[HTML][HTML] MiRNA transcriptome profiling of spheroid-enriched cells with cancer stem cell properties in human breast MCF-7 cell line
Breast cancer is the second leading cause of cancer-related mortality worldwide as most
patients often suffer cancer relapse. The reason is often attributed to the presence of cancer …
patients often suffer cancer relapse. The reason is often attributed to the presence of cancer …
Type-I collagen/collagenase modulates the 3D structure and behavior of glioblastoma spheroid models
Multicellular tumor spheroids have emerged as well-structured, three-dimensional culture
models that resemble and mimic the complexity of the dense and hypoxic cancer …
models that resemble and mimic the complexity of the dense and hypoxic cancer …
Effect of cationic charge density on transcytosis of polyethylenimine
The adsorption-mediated transcytosis (AMT) induced by the electrostatic interaction
between the positively charged surface of carriers and negatively charged cell membrane is …
between the positively charged surface of carriers and negatively charged cell membrane is …
EMT/MET at the crossroad of stemness, regeneration and oncogenesis: the ying-yang equilibrium recapitulated in cell spheroids
The epithelial-to-mesenchymal transition (EMT) is an essential trans-differentiation process,
which plays a critical role in embryonic development, wound healing, tissue regeneration …
which plays a critical role in embryonic development, wound healing, tissue regeneration …