Progress on the mechanism of natural products alleviating androgenetic alopecia

S Wu, X Kou, Y Niu, Y Liu, B Zheng, J Ma, M Liu… - European Journal of …, 2023 - Elsevier
Androgenetic alopecia (AGA) has become a widespread problem that leads to considerable
impairment of the psyche and daily life. The currently approved medications for the treatment …

The role of autophagy protein Atg5 in multiple sclerosis

ME Baeva, C Camara-Lemarroy - Multiple Sclerosis and Related Disorders, 2023 - Elsevier
Multiple sclerosis (MS) is a neurological disease which has a strong autoimmune
component to its pathology. Although there are currently many approved immunomodulatory …

miR-22a targets p62/SQSTM1 to negatively affect autophagy and disease resistance of grass carp (Ctenopharyngodon idella)

H Yu, L Xie, Z Chen, H Niu, X Jia, B Du, Y Shen… - Fish & Shellfish …, 2023 - Elsevier
MicroRNAs (miRNAs) are integral to many biological functions, including autophagy, a
process recently proven to be closely linked to innate immunity. In this study, we present …

PPARG-mediated autophagy activation alleviates inflammation in rheumatoid arthritis

Q Geng, J Xu, X Cao, Z Wang, Y Jiao, W Diao… - Journal of …, 2024 - Elsevier
Introduction Rheumatoid arthritis (RA) is a systemic inflammatory autoimmune disease
characterized by joint inflammation and bone damage, that not only restricts patient activity …

The multifaceted role of autophagy in skin autoimmune disorders: a guardian or culprit?

Y Lin, X Wu, Y Yang, Y Wu, L Xiang… - Frontiers in …, 2024 - frontiersin.org
Autophagy is a cellular process that functions to maintain intracellular homeostasis via the
degradation and recycling of defective organelles or damaged proteins. This dynamic …

Mechanistic role of quercetin as inhibitor for adenosine deaminase enzyme in rheumatoid arthritis: systematic review

A Atta, MM Salem, KS El-Said, TM Mohamed - Cellular & Molecular …, 2024 - Springer
Rheumatoid arthritis (RA) is an autoimmune disease involving T and B lymphocytes.
Autoantibodies contribute to joint deterioration and worsening symptoms. Adenosine …

Resveratrol attenuates inflammation and fibrosis in rheumatoid arthritis-associated interstitial lung disease via the AKT/TMEM175 pathway

N Liu, X Fan, Y Shao, S Chen, T Wang, T Yao… - Journal of Translational …, 2024 - Springer
Background and purpose Interstitial lung disease (ILD) represents a significant complication
of rheumatoid arthritis (RA) that lacks effective treatment options. This study aimed to …

Modes and Mechanisms of Salivary Gland Epithelial Cell Death in Sjogren's Syndrome

J Zhou, JL Pathak, Q Liu, S Hu, T Cao… - Advanced …, 2023 - Wiley Online Library
Sjogren's syndrome is an autoimmune disease in middle and old‐aged women with a dry
mucosal surface, which is caused by the dysfunction of secretory glands, such as the oral …

Single-cell transcriptional profiling reveals aberrant gene expression patterns and cell states in autoimmune diseases

Z Liu, W Wei, J Zhang, X Yang, Z Feng, B Zhang… - Molecular …, 2024 - Elsevier
Multiple sclerosis (MS), primary Sjögren syndrome (pSS), and systemic lupus erythematosus
(SLE) share numerous clinical symptoms and serological characteristics. We analyzed …

Association of autoimmune and allergic diseases with senile cataract: a bidirectional two-sample Mendelian randomization study

W Yuan, X Li, G Wang, B Qu, F Zhao - Frontiers in Immunology, 2024 - frontiersin.org
Background Many observational studies have been reported that patients with autoimmune
or allergic diseases seem to have a higher risk of developing senile cataract, but the views …