Oxidative stress in the pathophysiology of type 2 diabetes and related complications: Current therapeutics strategies and future perspectives
JS Bhatti, A Sehrawat, J Mishra, IS Sidhu… - Free Radical Biology …, 2022 - Elsevier
Abstract Type 2 diabetes (T2DM) is a persistent metabolic disorder rising rapidly worldwide.
It is characterized by pancreatic insulin resistance and β-cell dysfunction. Hyperglycemia …
It is characterized by pancreatic insulin resistance and β-cell dysfunction. Hyperglycemia …
[HTML][HTML] The key role of mitochondrial function in health and disease
I San-Millán - Antioxidants, 2023 - mdpi.com
The role of mitochondrial function in health and disease has become increasingly
recognized, particularly in the last two decades. Mitochondrial dysfunction as well as …
recognized, particularly in the last two decades. Mitochondrial dysfunction as well as …
[HTML][HTML] Mitochondrial dysfunction and oxidative stress in metabolic disorders—A step towards mitochondria based therapeutic strategies
Mitochondria are the powerhouses of the cell and are involved in essential functions of the
cell, including ATP production, intracellular Ca 2+ regulation, reactive oxygen species …
cell, including ATP production, intracellular Ca 2+ regulation, reactive oxygen species …
[HTML][HTML] Metabolic syndrome: risk factors, diagnosis, pathogenesis, and management with natural approaches
SM Mohamed, MA Shalaby, RA El-Shiekh… - Food Chemistry …, 2023 - Elsevier
Metabolic syndrome (MetS) is a bunch of metabolic defects comprising hypertension, insulin
resistance, visceral obesity, fatty liver, and atherogenic cardiovascular diseases. Lifestyle …
resistance, visceral obesity, fatty liver, and atherogenic cardiovascular diseases. Lifestyle …
Healthful aging mediated by inhibition of oxidative stress
SF Vatner, J Zhang, M Oydanich, T Berkman… - Ageing Research …, 2020 - Elsevier
The progressive increase in lifespan over the past century carries with it some adversity
related to the accompanying burden of debilitating diseases prevalent in the older …
related to the accompanying burden of debilitating diseases prevalent in the older …
[HTML][HTML] Quercetin as an agent for protecting the bone: a review of the current evidence
Quercetin is a flavonoid abundantly found in fruits and vegetables. It possesses a wide
spectrum of biological activities, thus suggesting a role in disease prevention and health …
spectrum of biological activities, thus suggesting a role in disease prevention and health …
Biomarkers of oxidative stress in metabolic syndrome and associated diseases
R Vona, L Gambardella, C Cittadini… - Oxidative medicine …, 2019 - Wiley Online Library
Metabolic syndrome (MS) represents worldwide public health issue characterized by a set of
cardiovascular risk factors including obesity, diabetes, dyslipidemia, hypertension, and …
cardiovascular risk factors including obesity, diabetes, dyslipidemia, hypertension, and …
Redox-and non-redox-metal-induced formation of free radicals and their role in human disease
Transition metal ions are key elements of various biological processes ranging from oxygen
formation to hypoxia sensing, and therefore, their homeostasis is maintained within strict …
formation to hypoxia sensing, and therefore, their homeostasis is maintained within strict …
Mitochondrial dysfunction in obesity
AH de Mello, AB Costa, JDG Engel, GT Rezin - Life sciences, 2018 - Elsevier
Obesity leads to various changes in the body. Among them, the existing inflammatory
process may lead to an increase in the production of reactive oxygen species (ROS) and …
process may lead to an increase in the production of reactive oxygen species (ROS) and …
[HTML][HTML] Metabolic syndrome, aging and involvement of oxidative stress
F Bonomini, LF Rodella, R Rezzani - Aging and disease, 2015 - ncbi.nlm.nih.gov
The prevalence of the metabolic syndrome, a cluster of cardiovascular risk factors
associated with obesity and insulin resistance, is dramatically increasing in Western and …
associated with obesity and insulin resistance, is dramatically increasing in Western and …