Sirtuins (SIRTs) are nicotine adenine dinucleotide (+)-dependent histone deacetylases
regulating critical signaling pathways in prokaryotes and eukaryotes, and are involved in …

Nuclear factor erythroid 2-related factor 2 (NRF2) is a transcription factor that regulates the
cellular defense against toxic and oxidative insults through the expression of genes involved …

Poultry in commercial settings are exposed to a range of stressors. A growing body of
information clearly indicates that excess ROS/RNS production and oxidative stress are …

Abstract Silent information regulator 1 (SIRT1) is a ubiquitously expressed protein and has
an intricate role in the pathology, progression, and treatment of several diseases. SIRT1 is a …

The transcription factor nuclear factor erythroid 2 (NF-E2)-related factor 2 (NRF2) is a central
regulator of redox, metabolic, and protein homeostasis that intersects with many other …

A complex antioxidant system has been developed in mammals to relieve oxidative stress.
However, excessive reactive species derived from oxygen and nitrogen may still lead to …

Background Fucoxanthin is a pigment present in diverse marine organisms such as micro
and macro-algae. The most relevant source of fucoxanthin has been described to be the …

Liver diseases are caused by different etiological agents, mainly alcohol consumption,
viruses, drug intoxication or malnutrition. Frequently, liver diseases are initiated by oxidative …

Nuclear factor erythroid 2‐related factor 2 (NRF2) is a master transcriptional regulator of
genes whose products defend our cells for toxic and oxidative insults. Although NRF2 …

Silymarin (SM), an extract from the Silybum marianum (milk thistle) plant containing various
flavonolignans (with silybin being the major one), has received a tremendous amount of …