[HTML][HTML] Endpoints for clinical trials in ophthalmology

L Schmetterer, H Scholl, G Garhöfer… - Progress in Retinal and …, 2023 - Elsevier
With the identification of novel targets, the number of interventional clinical trials in
ophthalmology has increased. Visual acuity has for a long time been considered the gold …

Enhanced medical diagnosis for dOCTors: a perspective of optical coherence tomography

R Leitgeb, F Placzek, E Rank, L Krainz… - Journal of …, 2021 - spiedigitallibrary.org
Significance: After three decades, more than 75,000 publications, tens of companies being
involved in its commercialization, and a global market perspective of about USD 1.5 billion …

Functional optical coherence tomography and photoacoustic microscopy imaging for zebrafish larvae

R Haindl, AJ Deloria, C Sturtzel, H Sattmann… - Biomedical Optics …, 2020 - opg.optica.org
We present a dual modality functional optical coherence tomography and photoacoustic
microscopy (OCT-PAM) system. The photoacoustic modality employs an akinetic optical …

Advances in Doppler optical coherence tomography and angiography

Y Li, J Chen, Z Chen - Translational biophotonics, 2019 - Wiley Online Library
Since the first demonstration of Doppler optical coherence tomography (OCT) in 1997,
several functional extensions of Doppler OCT have been developed, including velocimetry …

Experimental methods for flow and aerosol measurements in human airways and their replicas

F Lizal, J Jedelsky, K Morgan, K Bauer, J Llop… - European Journal of …, 2018 - Elsevier
Recent developments in the prediction of local aerosol deposition in human lungs are driven
by the fast development of computational simulations. Although such simulations provide …

OCT-based velocimetry for blood flow quantification

B Braaf, MGO Gräfe, N Uribe-Patarroyo… - High resolution imaging …, 2019 - Springer
Current clinically available OCTA imaging methods are able to reliably distinguish retinal
regions of significant flow from static tissue by evaluating the backscattered OCT signal from …

Retinal blood flow speed quantification at the capillary level using temporal autocorrelation fitting OCTA

Y Hwang, J Won, A Yaghy, H Takahashi… - Biomedical Optics …, 2023 - opg.optica.org
Optical coherence tomography angiography (OCTA) can visualize vasculature structures,
but provides limited information about blood flow speed. Here, we present a second …

Retinal oxygen extraction in patients with primary open-angle glaucoma

G Garhöfer, AM Bata, A Popa-Cherecheanu… - International Journal of …, 2022 - mdpi.com
Objective: To compare total retinal oxygen extraction between patients with primary open-
angle glaucoma (POAG) and healthy control subjects. Design: A prospective, single-center …

Optic nerve head and retinal blood flow regulation during isometric exercise as assessed with laser speckle flowgraphy

KJ Witkowska, AM Bata, G Calzetti, N Luft, K Fondi… - PloS one, 2017 - journals.plos.org
The aim of the present study was to investigate regulation of blood flow (BF) in the optic
nerve head (ONH) and a peripapillary region (PPR) during an isometric exercise-induced …

Age-related decline of retinal oxygen extraction in healthy subjects

AM Bata, K Fondi, S Szegedi… - … & visual science, 2019 - iovs.arvojournals.org
Purpose: To investigate the age-dependence of total retinal blood flow and total retinal
oxygen extraction in healthy subjects and determine their possible correlations with …